Wendy E Hague, John Simes, Adrienne Kirby, Anthony C Keech, Harvey D White, David Hunt, Paul J Nestel, David M Colquhoun, Helen Pater, Ralph A Stewart, David R Sullivan, Peter L Thompson, Malcolm West, Paul P Glasziou, Andrew M Tonkin
BACKGROUND: We aimed to assess the long-term effects of treatment with statin therapy on all-cause mortality, cause-specific mortality, and cancer incidence from extended follow-up of the Long-term Intervention with Pravastatin in Ischemic Disease (LIPID) trial. METHODS AND RESULTS: LIPID initially compared pravastatin and placebo over 6 years in 9014 patients with previous coronary heart disease. After the double-blind period, all patients were offered open-label statin therapy...
May 10, 2016: Circulation