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Role of Troponin in Patients With Chronic Kidney Disease and Suspected Acute Coronary Syndrome

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Sylvie R Stacy, Catalina Suarez-Cuervo, Zackary Berger, Lisa M Wilson, Hsin-Chieh Yeh, Eric B Bass, Erin D Michos
BACKGROUND: Patients with chronic kidney disease (CKD) have high prevalence of elevated serum troponin levels, which makes diagnosis of acute coronary syndrome (ACS) challenging. PURPOSE: To evaluate the utility of troponin in ACS diagnosis, treatment, and prognosis among patients with CKD. DATA SOURCES: MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials through May 2014. STUDY SELECTION: Studies examining elevated versus normal troponin levels in terms of their diagnostic performance in detection of ACS, effect on ACS management strategies, and prognostic value for mortality or cardiovascular events after ACS among patients with CKD...
October 7, 2014: Annals of Internal Medicine
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