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Therapy

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By ZS Bao
https://www.readbyqxmd.com/read/25087230/new-concepts-in-the-management-of-diffuse-low-grade-glioma-proposal-of-a-multistage-and-individualized-therapeutic-approach
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REVIEW
Hugues Duffau, Luc Taillandier
Diffuse low-grade glioma grows, migrates along white matter tracts, and progresses to high-grade glioma. Rather than a "wait and see" policy, an aggressive attitude is now recommended, with early surgery as the first therapy. Intraoperative mapping, with maximal resection according to functional boundaries, is associated with a longer overall survival (OS) while minimizing morbidity. However, most studies have investigated the role of only one specific treatment (surgery, radiotherapy, chemotherapy) without taking a global view of managing the cumulative time while preserving quality of life (QoL) versus time to anaplastic transformation...
March 2015: Neuro-oncology
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