collection
MENU ▼
Read by QxMD icon Read
search

Esteroids and newborn

shared collection
3 papers 0 to 25 followers
https://www.readbyqxmd.com/read/26351971/intratracheal-administration-of-budesonide-surfactant-to-prevent-bronchopulmonary-dysplasia
#1
RANDOMIZED CONTROLLED TRIAL
Tsu F Yeh, Chung M Chen, Shou Y Wu, Zahid Husan, Tsai C Li, Wu S Hsieh, Chang H Tsai, Hung C Lin
RATIONALE: Bronchopulmonary dysplasia (BPD) is an important complication of mechanical ventilation in preterm infants, and no definite therapy can eliminate this complication. Pulmonary inflammation plays a crucial role in its pathogenesis, and glucocorticoid is one potential therapy to prevent BPD. OBJECTIVES: To compare the effect of intratracheal administration of surfactant/budesonide with that of surfactant alone on the incidence of death or BPD. METHODS: A clinical trial was conducted in three tertiary neonatal centers in the United States and Taiwan, in which 265 very-low-birth-weight infants with severe respiratory distress syndrome who required mechanical ventilation and inspired oxygen (fraction of inspired oxygen, ≥50%) within 4 hours of birth were randomly assigned to one of two groups (131 intervention and 134 control)...
January 1, 2016: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/25301528/duration-of-gestation-and-mode-of-delivery-affect-the-genes-of-transepithelial-sodium-transport-in-pulmonary-adaptation
#2
Cecilia Janér, Olli M Pitkänen, Liina Süvari, Ursula Turpeinen, Anniina Palojärvi, Sture Andersson, Otto Helve
BACKGROUND: Respiratory distress due to inadequate lung liquid clearance is a significant problem in infants delivered late preterm or early term, especially by elective cesarean delivery (CD). Lung liquid clearance depends on epithelial ion transport and in animals is induced by glucocorticoids. OBJECTIVES: In newborn late preterm and term infants to study airway epithelial gene expressions of epithelial sodium channel (ENaC), and the serum and glucocorticoid-inducible kinase 1 (SGK1), and their association with cortisol, mode of delivery, and gestational age (GA)...
2015: Neonatology
https://www.readbyqxmd.com/read/25078865/neurodevelopmental-impact-of-hydrocortisone-exposure-in-extremely-low-birth-weight-infants-outcomes-at-1-and-2-years
#3
K Patra, M M Greene, J M Silvestri
OBJECTIVE: Postnatal steroids are used in neonatal intensive care units despite known side effects. Hydrocortisone (HC) use persists as it is believed to have less deleterious effects on neurodevelopmental (ND) outcome compared to other steroids. The literature is sparse with respect to the ND impact of HC use in recent years. Hence, we sought to examine the effect of HC use on ND outcome in a contemporary cohort of extremely low birth weight (ELBW) infants. STUDY DESIGN: A total of 175 ELBW infants (86 HC exposed, 89 steroid naive) born in 2008 to 2010 were compared for mortality, morbidity and ND outcome at 8 and 20 months corrected age...
January 2015: Journal of Perinatology: Official Journal of the California Perinatal Association
1
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"