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Bmp with polymers

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Yen-Chen Huang, Darnell Kaigler, Kevin G Rice, Paul H Krebsbach, David J Mooney
UNLABELLED: Bone formation is a coordinated process involving various biological factors. We have developed a scaffold system capable of sustained and localized presentation of osteogenic (BMP-4) and angiogenic (VEGF) growth factors and human bone marrow stromal cells to promote bone formation at an ectopic site. Combined delivery of these factors significantly enhanced bone formation compared with other conditions. INTRODUCTION: Tissue regeneration entails complex interactions between multiple signals and materials platforms...
May 2005: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
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