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285 papers 1000+ followers Papers on everything from maintainance fluids to transfusion
By Faye Kehler Family Physician and GP Anesthetist since 1987 interested in all aspects of Medicine
https://www.readbyqxmd.com/read/27798738/fluid-management-in-the-icu-has-the-tide-turned
#1
EDITORIAL
Peter Buhl Hjortrup, Anthony Delaney
No abstract text is available yet for this article.
October 31, 2016: Intensive Care Medicine
https://www.readbyqxmd.com/read/23749153/half-molar-sodium-lactate-infusion-to-prevent-intracranial-hypertensive-episodes-in-severe-traumatic-brain-injured-patients-a-randomized-controlled-trial
#2
RANDOMIZED CONTROLLED TRIAL
Carole Ichai, Jean-François Payen, Jean-Christophe Orban, Hervé Quintard, Hubert Roth, Robin Legrand, Gilles Francony, Xavier M Leverve
PURPOSE: Preventive treatments of traumatic intracranial hypertension are not yet established. We aimed to compare the efficiency of half-molar sodium lactate (SL) versus saline serum solutions in preventing episodes of raised intracranial pressure (ICP) in patients with severe traumatic brain injury (TBI). METHODS: This was a double-blind, randomized controlled trial including 60 patients with severe TBI requiring ICP monitoring. Patients were randomly allocated to receive a 48-h continuous infusion at 0...
August 2013: Intensive Care Medicine
https://www.readbyqxmd.com/read/24979716/intravenous-fluids-in-traumatic-brain-injury-what-s-the-solution
#3
REVIEW
Dashiell Gantner, Elizabeth M Moore, D James Cooper
PURPOSE OF REVIEW: Intravenous fluid is a fundamental component of trauma care and fluid management influences patient outcomes. This narrative review appraises recent clinical studies of fluid therapy in patients with traumatic brain injury (TBI), with respect to its use in volume resuscitation and prevention of secondary injury. RECENT FINDINGS: Despite the development of level 1 evidence in fluid resuscitation, in patients with TBI key questions concerning optimal composition and volume remain unanswered...
August 2014: Current Opinion in Critical Care
https://www.readbyqxmd.com/read/25058216/effect-of-erythropoietin-and-transfusion-threshold-on-neurological-recovery-after-traumatic-brain-injury-a-randomized-clinical-trial
#4
RANDOMIZED CONTROLLED TRIAL
Claudia S Robertson, H Julia Hannay, José-Miguel Yamal, Shankar Gopinath, J Clay Goodman, Barbara C Tilley, Athena Baldwin, Lucia Rivera Lara, Hector Saucedo-Crespo, Osama Ahmed, Santhosh Sadasivan, Luciano Ponce, Jovanny Cruz-Navarro, Hazem Shahin, Imoigele P Aisiku, Pratik Doshi, Alex Valadka, Leslie Neipert, Jace M Waguspack, M Laura Rubin, Julia S Benoit, Paul Swank
IMPORTANCE: There is limited information about the effect of erythropoietin or a high hemoglobin transfusion threshold after a traumatic brain injury. OBJECTIVE: To compare the effects of erythropoietin and 2 hemoglobin transfusion thresholds (7 and 10 g/dL) on neurological recovery after traumatic brain injury. DESIGN, SETTING, AND PARTICIPANTS: Randomized clinical trial of 200 patients (erythropoietin, n = 102; placebo, n = 98) with closed head injury who were unable to follow commands and were enrolled within 6 hours of injury at neurosurgical intensive care units in 2 US level I trauma centers between May 2006 and August 2012...
July 2, 2014: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/27592289/echocardiography-as-a-guide-for-fluid-management
#5
REVIEW
John H Boyd, Demetrios Sirounis, Julien Maizel, Michel Slama
BACKGROUND: In critically ill patients at risk for organ failure, the administration of intravenous fluids has equal chances of resulting in benefit or harm. While the intent of intravenous fluid is to increase cardiac output and oxygen delivery, unwelcome results in those patients who do not increase their cardiac output are tissue edema, hypoxemia, and excess mortality. Here we briefly review bedside methods to assess fluid responsiveness, focusing upon the strengths and pitfalls of echocardiography in spontaneously breathing mechanically ventilated patients as a means to guide fluid management...
September 4, 2016: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/27484681/fluid-overload-in-the-icu-evaluation-and-management
#6
Rolando Claure-Del Granado, Ravindra L Mehta
BACKGROUND: Fluid overload is frequently found in acute kidney injury patients in critical care units. Recent studies have shown the relationship of fluid overload with adverse outcomes; hence, manage and optimization of fluid balance becomes a central component of the management of critically ill patients. DISCUSSION: In critically ill patients, in order to restore cardiac output, systemic blood pressure and renal perfusion an adequate fluid resuscitation is essential...
August 2, 2016: BMC Nephrology
https://www.readbyqxmd.com/read/27536694/fluid-management-for-critically-ill-patients-a-review-of-the-current-state-of-fluid-therapy-in-the-intensive-care-unit
#7
REVIEW
Erin Frazee, Kianoush Kashani
BACKGROUND: Intravenous fluids (IVF) are frequently utilized to restore intravascular volume in patients with distributive and hypovolemic shock. Although the benefits of the appropriate use of fluids in intensive care units (ICUs) and hospitals are well described, there is growing knowledge regarding the potential risks of volume overload and its impact on organ failure and mortality. To avoid volume overload and its associated complications, strategies to identify fluid responsiveness are developed and utilized more often among ICU patients...
June 2016: Kidney Diseases
https://www.readbyqxmd.com/read/27229641/sepsis-resuscitation-fluid-choice-and-dose
#8
REVIEW
Matthew W Semler, Todd W Rice
Sepsis is a common and life-threatening inflammatory response to severe infection treated with antibiotics and fluid resuscitation. Despite the central role of intravenous fluid in sepsis management, fundamental questions regarding which fluid and in what amount remain unanswered. Recent advances in understanding the physiologic response to fluid administration, and large clinical studies examining resuscitation strategies, fluid balance after resuscitation, colloid versus crystalloid solutions, and high- versus low-chloride crystalloids, inform the current approach to sepsis fluid management and suggest areas for future research...
June 2016: Clinics in Chest Medicine
https://www.readbyqxmd.com/read/26945358/impact-of-albumin-on-coagulation-competence-and-hemorrhage-during-major-surgery-a-randomized-controlled-trial
#9
RANDOMIZED CONTROLLED TRIAL
Kirsten C Rasmussen, Michael Højskov, Pär I Johansson, Irina Kridina, Thomas Kistorp, Lisbeth Salling, Henning B Nielsen, Birgitte Ruhnau, Tom Pedersen, Niels H Secher
For patients exposed to a massive blood loss during surgery, maintained coagulation competence is important. It is less obvious whether coagulation competence influences bleeding during elective surgery where patients are exposed to infusion of a crystalloid or a colloid. This randomized controlled trial evaluates whether administration of 5% human albumin (HA) or lactated Ringer solution (LR) affects coagulation competence and in turn blood loss during cystectomy due to bladder cancer. Forty patients undergoing radical cystectomy were included to receive either 5% HA (n = 20) or LR (n = 20)...
March 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/26974423/comparative-evaluation-of-crystalloid-resuscitation-rate-in-a-human-model-of-compensated-haemorrhagic-shock
#10
Loretta Ho, Lawrence Lau, Leonid Churilov, Bernhard Riedel, Larry McNicol, Robert G Hahn, Laurence Weinberg
INTRODUCTION: The most effective rate of fluid resuscitation in haemorrhagic shock is unknown. METHODS: We performed a randomized crossover pilot study in a healthy volunteer model of compensated haemorrhagic shock. Following venesection of 15 mL/kg of blood, participants were randomized to 20 mL/kg of crystalloid over 10 min (FAST treatment) or 30 min (SLOW treatment). The primary end point was oxygen delivery (DO2). Secondary end points included pressure and flow-based haemodynamic variables, blood volume expansion, and clinical biochemistry...
August 2016: Shock
https://www.readbyqxmd.com/read/26976277/crystalloid-fluid-therapy
#11
REVIEW
Sumeet Reddy, Laurence Weinberg, Paul Young
This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency medicine 2016. Other selected articles can be found online at http://www.biomedcentral.com/collections/annualupdate2016. Further information about the Annual Update in Intensive Care and Emergency Medicine is available from http://www.springer.com/series/8901.
March 15, 2016: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/26981172/human-albumin-solution-for-patients-with-cirrhosis-and-acute-on-chronic-liver-failure-beyond-simple-volume-expansion
#12
REVIEW
Christopher Valerio, Eleni Theocharidou, Andrew Davenport, Banwari Agarwal
To provide an overview of the properties of human serum albumin (HSA), and to review the evidence for the use of human albumin solution (HAS) in critical illness, sepsis and cirrhosis. A MEDLINE search was performed using the terms "human albumin", "critical illness", "sepsis" and "cirrhosis". The references of retrieved articles were reviewed manually. Studies published between 1980 and 2014 were selected based on quality criteria. Data extraction was performed by all authors. HSA is the main plasma protein contributing greatly to its oncotic pressure...
March 8, 2016: World Journal of Hepatology
https://www.readbyqxmd.com/read/27021127/modified-traumatic-bleeding-severity-score-early-determination-of-the-need-for-massive-transfusion
#13
Takayuki Ogura, Alan Kawarai Lefor, Mamoru Masuda, Shigeki Kushimoto
BACKGROUND: Determination of the need for massive transfusion (MT) is essential for early activation of a MT protocol. The Traumatic Bleeding Severity Score (TBSS) predicts the need for MT accurately, but takes time to determine because systolic blood pressure after a 1000mL of crystalloid infusion is used. The aim of this study is to determine the how well the Modified TBSS (age, sonography, pelvic fracture, serum lactate and systolic blood pressure on arrival) predicts the need for MT (accuracy)...
June 2016: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27048395/prehospital-volume-resuscitation-did-evidence-defeat-the-crystalloid-dogma-an-analysis-of-the-traumaregister-dgu%C3%A2-2002-2012
#14
Arne Driessen, Matthias Fröhlich, Nadine Schäfer, Manuel Mutschler, Jerome M Defosse, Thomas Brockamp, Bertil Bouillon, Ewa K Stürmer, Rolf Lefering, Marc Maegele
BACKGROUND: Various studies have shown the deleterious effect of high volume resuscitation following severe trauma promoting coagulopathy by haemodilution, acidosis and hypothermia. As the optimal resuscitation strategy during prehospital trauma care is still discussed, we raised the question if the amount and kind of fluids administered changed over the recent years. Further, if less volume was administered, fewer patients should have arrived in coagulopathic depletion in the Emergency Department resulting in less blood product transfusions...
April 6, 2016: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
https://www.readbyqxmd.com/read/27058509/the-half-life-of-infusion-fluids-an-educational-review
#15
Robert G Hahn, Gordon Lyons
An understanding of the half-life (T1/2) of infused fluids can help prevent iatrogenic problems such as volume overload and postoperative interstitial oedema. Simulations show that a prolongation of the T1/2 for crystalloid fluid increases the plasma volume and promotes accumulation of fluid in the interstitial fluid space. The T1/2 for crystalloids is usually 20 to 40 min in conscious humans but might extend to 80 min or longer in the presence of preoperative stress, dehydration, blood loss of <1 l or pregnancy...
July 2016: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/27077832/evaluation-of-the-early-use-of-albumin-in-children-with-extensive-burns-a-randomized-controlled-trial
#16
Maria Helena Müller Dittrich, Werther Brunow de Carvalho, Edson Lopes Lavado
OBJECTIVE: To compare early versus delayed albumin resuscitation in children with burns in terms of clinical outcome and response. DESIGN: Randomized controlled trial. SETTING: Burn center at a tertiary care teaching hospital. PATIENTS: Forty-six children aged 1-12 years with burns greater than 15-45% total body surface area admitted within 12 hours of burn injury. INTERVENTIONS: Fluid resuscitation was based on the Parkland formula (3 mL/kg/% total body surface area), adjusted according to urine output...
June 2016: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/27085369/association-of-fluid-resuscitation-initiation-within-30-minutes-of%C3%A2-severe-sepsis-and-septic-shock-recognition-with-reduced%C3%A2-mortality-and-length-of-stay
#17
Daniel Leisman, Benjamin Wie, Martin Doerfler, Andrea Bianculli, Mary Frances Ward, Meredith Akerman, John K D'Angelo, Jason A Zemmel D'Amore
STUDY OBJECTIVE: We evaluate the association of intravenous fluid resuscitation initiation within 30 minutes of severe sepsis or septic shock identification in the emergency department (ED) with inhospital mortality and hospital length of stay. We also compare intravenous fluid resuscitation initiated at various times from severe sepsis or septic shock identification's association with the same outcomes. METHODS: This was a review of a prospective, observational cohort of all ED severe sepsis or septic shock patients during 13 months, captured in a performance improvement database at a single, urban, tertiary care facility (90,000 ED visits/year)...
September 2016: Annals of Emergency Medicine
https://www.readbyqxmd.com/read/27087980/fluid-therapy-in-the-perioperative-setting-a-clinical-review
#18
REVIEW
Anders Winther Voldby, Birgitte Brandstrup
BACKGROUND: Perioperative hypovolemia and fluid overload have effects on both complications following surgery and on patient survival. Therefore, the administration of intravenous fluids before, during, and after surgery at the right time and in the right amounts is of great importance. This review aims to analyze the literature concerning perioperative fluid therapy in abdominal surgery and to provide evidence-based recommendations for clinical practice. RESULTS: Preoperative oral or intravenous administration of carbohydrate containing fluids has been shown to improve postoperative well-being and muscular strength and to reduce insulin resistance...
2016: Journal of Intensive Care
https://www.readbyqxmd.com/read/27113691/fluid-as-a-drug-balancing-resuscitation-and-fluid-overload-in-the-intensive-care-setting
#19
REVIEW
Matthew D McGuire, Michael Heung
Intravenous fluid resuscitation is ubiquitous throughout medicine and is often considered a benign procedure. Yet, there is now clear recognition of the potential harms of fluid overload after initial resuscitation. In recent years, there has also been an increasing focus on comparing various resuscitation fluids with respect to both benefits and risks. Studies have examined colloids, such as albumin and starches, against the clinical standard of crystalloids. In addition, evidence has emerged to suggest that outcomes may be different between resuscitation with chloride-rich vs balanced crystalloid solutions...
May 2016: Advances in Chronic Kidney Disease
https://www.readbyqxmd.com/read/27153047/saline-is-the-solution-for-crystalloid-resuscitation
#20
Paul Young
No abstract text is available yet for this article.
August 2016: Critical Care Medicine
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