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LNH Burkitt y tto baja intensidad en Adultos. NEJM 2013.

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By Manuel Leonidas Rosales Acevedo M├ędico hematologo
Kieron Dunleavy, Stefania Pittaluga, Margaret Shovlin, Seth M Steinberg, Diane Cole, Cliona Grant, Brigitte Widemann, Louis M Staudt, Elaine S Jaffe, Richard F Little, Wyndham H Wilson
BACKGROUND: Burkitt's lymphoma is an aggressive B-cell lymphoma that occurs in children and adults and is largely curable with the use of intensive and toxic chemotherapy. Current treatments are less effective and have more severe side effects in adults and patients with immunodeficiency than in children. METHODS: We studied low-intensity treatment consisting of infused etoposide, doxorubicin, and cyclophosphamide with vincristine, prednisone, and rituximab (EPOCH-R) in patients with untreated Burkitt's lymphoma...
November 14, 2013: New England Journal of Medicine
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