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LH, Review. CROH 2013.

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By Manuel Leonidas Rosales Acevedo Médico hematologo
Paolo G Gobbi, Andrés J M Ferreri, Maurilio Ponzoni, Alessandro Levis
Hodgkin lymphoma (HL) is a curable malignancy which shows a bimodal curve in incidence in economically developed countries; there is a putative association with Epstein-Barr virus. The WHO 2008 classification schema recognises two histological types of HL: the nodular lymphocyte predominant and the "classic" HL. The latter encompasses four entities: nodular sclerosis, mixed cellularity, lymphocyte depletion, and lymphocyte-rich. Most patients with HL present with asymptomatic superficial lymphadenopathy. The commonest sites of disease are the cervical, supraclavicular and mediastinal lymph nodes, while sub-diaphragmatic presentations and bone marrow and hepatic involvement are less common...
February 2013: Critical Reviews in Oncology/hematology
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