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https://www.readbyqxmd.com/read/30072808/introduction-to-neonatologist-performed-echocardiography
#1
REVIEW
Alan M Groves, Yogen Singh, Eugene Dempsey, Zoltan Molnar, Topun Austin, Afif El-Khuffash, Willem P de Boode
Cardiac ultrasound techniques are increasingly used in the neonatal intensive care unit to guide cardiorespiratory care of the sick newborn. This is the first in a series of eight review articles discussing the current status of "neonatologist-performed echocardiography" (NPE). The aim of this introductory review is to discuss four key elements of NPE. Indications for scanning are summarized to give the neonatologist with echocardiography skills a clear scope of practice. The fundamental physics of ultrasound are explained to allow for image optimization and avoid erroneous conclusions from artifacts...
July 2018: Pediatric Research
https://www.readbyqxmd.com/read/30314974/is-preterm-nutrition-a-trade-off-between-head-and-heart
#2
EDITORIAL
Gopi Menon, Angela L Davidson, Amanda Jane Drake, Nicholas D Embleton
No abstract text is available yet for this article.
October 12, 2018: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/30193751/persistent-hypoglycemia-in-children-targeted-gene-panel-improves-the-diagnosis-of-hypoglycemia-due-to-inborn-errors-of-metabolism
#3
Emanuela Ponzi, Arianna Maiorana, Francesca Romana Lepri, Mafalda Mucciolo, Michela Semeraro, Roberta Taurisano, Giorgia Olivieri, Antonio Novelli, Carlo Dionisi-Vici
OBJECTIVES: To evaluate the role of next generation sequencing in genetic diagnosis of pediatric patients with persistent hypoglycemia. STUDY DESIGN: Sixty-four patients investigated through an extensive workup were divided in 3 diagnostic classes based on the likelihood of a genetic diagnosis: (1) single candidate gene (9/64); (2) multiple candidate genes (43/64); and (3) no candidate gene (12/64). Subsequently, patients were tested through a custom gene panel of 65 targeted genes, which included 5 disease categories: (1) hyperinsulinemic hypoglycemia, (2) fatty acid-oxidation defects and ketogenesis defects, (3) ketolysis defects, (4) glycogen storage diseases and other disorders of carbohydrate metabolism, and (5) mitochondrial disorders...
November 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29984201/acute-respiratory-distress-syndrome-an-update-and-review
#4
Gautam Rawal, Sankalp Yadav, Raj Kumar
Acute respiratory distress syndrome (ARDS) is a life threatening condition characterized by severe hypoxemia due to pulmonary gas exchange failure and was first recognized in 1960s.Since its first description, it has undergone intensive research in the past few decades to understand its pathogenesis and therapies. Despite this, the recommended therapies to decrease mortality in ARDS remain limited and include low-tidal volume mechanical ventilation, prone ventilation and recently, the ECMO rescue therapy in extreme cases...
June 2018: Journal of Translational Internal Medicine
https://www.readbyqxmd.com/read/29955859/a-guide-to-utilization-of-the-microbiology-laboratory-for-diagnosis-of-infectious-diseases-2018-update-by-the-infectious-diseases-society-of-america-and-the-american-society-for-microbiology
#5
J Michael Miller, Matthew J Binnicker, Sheldon Campbell, Karen C Carroll, Kimberle C Chapin, Peter H Gilligan, Mark D Gonzalez, Robert C Jerris, Sue C Kehl, Robin Patel, Bobbi S Pritt, Sandra S Richter, Barbara Robinson-Dunn, Joseph D Schwartzman, James W Snyder, Sam Telford, Elitza S Theel, Richard B Thomson, Melvin P Weinstein, Joseph D Yao
The critical nature of the microbiology laboratory in infectious disease diagnosis calls for a close, positive working relationship between the physician/advanced practice provider and the microbiologists who provide enormous value to the healthcare team. This document, developed by experts in laboratory and adult and pediatric clinical medicine, provides information on which tests are valuable and in which contexts, and on tests that add little or no value for diagnostic decisions. This document presents a system-based approach rather than specimen-based approach, and includes bloodstream and cardiovascular system infections, central nervous system infections, ocular infections, soft tissue infections of the head and neck, upper and lower respiratory infections, infections of the gastrointestinal tract, intra-abdominal infections, bone and joint infections, urinary tract infections, genital infections, and other skin and soft tissue infections; or into etiologic agent groups, including arthropod-borne infections, viral syndromes, and blood and tissue parasite infections...
August 31, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29808264/neonatal-hypertension-cases-causes-and-clinical-approach
#6
Michelle C Starr, Joseph T Flynn
Neonatal hypertension is increasingly recognized as dramatic improvements in neonatal intensive care, advancements in our understanding of neonatal physiology, and implementation of new therapies have led to improved survival of premature infants. A variety of factors appear to be important in determining blood pressure in neonates, including gestational age, birth weight, and postmenstrual age. Normative data on neonatal blood pressure values remain limited. The cause of hypertension in an affected neonate is often identified with careful diagnostic evaluation, with the most common causes being umbilical catheter-associated thrombosis, renal parenchymal disease, and chronic lung disease...
May 28, 2018: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/30006471/the-secret-sauce-secrets-of-high-performing-neonatal-intensive-care-units
#7
EDITORIAL
Lamia Soghier, Billie Lou Short
No abstract text is available yet for this article.
July 13, 2018: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/29768264/opportunities-and-challenges-in-global-perinatal-research
#8
Jessica Duby, Renee Sharma, Zulfiqar A Bhutta
BACKGROUND: The global plight of stillbirths and neonatal mortality is concentrated in low- and middle-income countries. The ambitious targets introduced by the World Health Organization in the Every Newborn Action Plan demand a commitment to research that promotes equitable perinatal outcomes. OBJECTIVES: The aim of this review was to understand the opportunities for global perinatal research and the accompanying challenges. METHODS: We conducted a literature search to identify research prioritization exercises from 2014 to 2018 pertaining to global perinatal health...
2018: Neonatology
https://www.readbyqxmd.com/read/29847833/in-preterm-infants-length-growth-below-expected-growth-during-hospital-stay-predicts-poor-neurodevelopment-at-2-years
#9
Laure Simon, Camille Théveniaut, Cyril Flamant, Anne Frondas-Chauty, Dominique Darmaun, Jean-Christophe Rozé
BACKGROUND: In preterm infants, neonatal weight growth is associated with neurodevelopmental outcome but is a poor indicator of growth quality. OBJECTIVE: The aim of this work was to measure the relationship between neonatal length growth and the 2-year neurological outcome in preterm infants. METHODS: A total of 2,403 infants enrolled in the LIFT cohort with gestational age less than 34 weeks were studied. Neonatal observed length growth (OLG) was calculated as the change in length Z-score between birth and discharge...
2018: Neonatology
https://www.readbyqxmd.com/read/29895007/the-postnatal-glucose-concentration-nadir-is-not-abnormal-and-does-not-need-to-be-treated
#10
LETTER
William W Hay, David H Adamkin, Jane E Harding, Jane Hawdon
No abstract text is available yet for this article.
2018: Neonatology
https://www.readbyqxmd.com/read/29898454/neonates-at-risk-of-early-onset-sepsis-which-is-the-best-approach
#11
Alberto Berardi, Caterina Spada, Maria Grazia Capretti, Matilde Ciccia, Maria Rita Pulvirenti, Martina Vezzosi, Fabrizio Sandri
No abstract text is available yet for this article.
2018: Neonatology
https://www.readbyqxmd.com/read/29626072/improving-endotracheal-tube-placement-in-neonates
#12
LETTER
Anip Garg, Ajay Kumar Sinha, Stephen Terence Kempley
No abstract text is available yet for this article.
July 2018: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/29406009/use-of-glucocorticoids-for-the-fetus-and-preterm-infant
#13
REVIEW
Susan M Scott, Susan R Rose
The soon-to-be-delivered fetus and preterm infant have been treated with glucocorticoids to prepare for postnatal life, historically for more than 40 years. The use of glucocorticoids is as much for replacement of cortisol in the setting of a poorly functioning hypothalamic-pituitary-adrenal axis in the preterm infant, as it is for prevention of long-term lung dysfunction. Potential negative effects of glucocorticoid treatment on brain development and function have been observed more often with dexamethasone therapy than with use of other glucocorticoids...
March 2018: Clinics in Perinatology
https://www.readbyqxmd.com/read/29747882/antenatal-corticosteroids-who-should-we-be-treating
#14
REVIEW
Whitney A Booker, Cynthia Gyamfi-Bannerman
Antenatal corticosteroids remain one of the crucial interventions in those at risk for imminent preterm birth. Therapeutic benefits include reducing major complications of prematurity such as respiratory distress syndrome, intraventricular hemorrhage, and necrotizing enterocolitis, as well as an overall decrease in neonatal deaths. Optimal reductions in neonatal morbidity and mortality require a thoughtful review of the timing of administration. In addition, a thorough understanding is required of which patients maximally benefit from this intervention in the management and counseling of those at risk for preterm birth...
June 2018: Clinics in Perinatology
https://www.readbyqxmd.com/read/29747884/perinatal-care-of-infants-with-congenital-birth-defects
#15
REVIEW
Elizabeth K Sewell, Sarah Keene
Prenatal diagnosis has changed perinatal medicine dramatically, allowing for additional fetal monitoring, referral and counseling, delivery planning, the option of fetal intervention, and targeted postnatal management. Teams participating in the delivery room care of infants with known anomalies should be knowledgeable about specific needs and expectations but also ready for unexpected complications. A small number of neonates will need rapid access to postnatal interventions, such as surgery, but most can be stabilized with appropriate neonatal care...
June 2018: Clinics in Perinatology
https://www.readbyqxmd.com/read/29747885/prognosis-as-an-intervention
#16
REVIEW
Matthew A Rysavy
This article elaborates on how neonatologists and perinatologists might conceive of prognosis as an intervention with outcomes relevant to patients, families, and society at large and highlights aspects of this important area of practice requiring further study.
June 2018: Clinics in Perinatology
https://www.readbyqxmd.com/read/29747887/preventing-continuous-positive-airway-pressure-failure-evidence-based-and-physiologically-sound-practices-from-delivery-room-to-the-neonatal-intensive-care-unit
#17
REVIEW
Clyde J Wright, Laurie G Sherlock, Rakesh Sahni, Richard A Polin
Routine use of continuous positive airway pressure (CPAP) to support preterm infants with respiratory distress is an evidenced-based strategy to decrease incidence of bronchopulmonary dysplasia. However, rates of CPAP failure remain unacceptably high in very premature neonates, who are at high risk for developing bronchopulmonary dysplasia. Using the GRADE framework to assess the quality of available evidence, this article reviews strategies aimed at decreasing CPAP failure, starting with delivery room interventions and followed through to system-based efforts in the neonatal intensive care unit...
June 2018: Clinics in Perinatology
https://www.readbyqxmd.com/read/29747888/optimizing-caffeine-use-and-risk-of-bronchopulmonary-dysplasia-in-preterm-infants-a-systematic-review-meta-analysis-and-application-of-grading-of-recommendations-assessment-development-and-evaluation-methodology
#18
REVIEW
Mitali Atul Pakvasa, Vivek Saroha, Ravi Mangal Patel
Caffeine reduces the risk of bronchopulmonary dysplasia (BPD). Optimizing caffeine use could increase therapeutic benefit. We performed a systematic-review and random-effects meta-analysis of studies comparing different timing of initiation and dose of caffeine on the risk of BPD. Earlier initiation, compared to later, was associated with a decreased risk of BPD (5 observational studies; n = 63,049, adjusted OR 0.69; 95% CI 0.64-0.75, GRADE: low quality). High-dose caffeine, compared to standard-dose, was associated with a decreased risk of BPD (3 randomized trials, n = 432, OR 0...
June 2018: Clinics in Perinatology
https://www.readbyqxmd.com/read/29927534/mobile-phone-innovations-for-maternal-and-neonatal-health-in-low-and-middle-income-countries-the-role-of-mhealth
#19
S Lund
No abstract text is available yet for this article.
November 2018: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29784044/work-stress-prevention-needs-of-employees-and-supervisors
#20
Bo M Havermans, Evelien P M Brouwers, Rianne J A Hoek, Johannes R Anema, Allard J van der Beek, Cécile R L Boot
BACKGROUND: Work stress prevention can reduce health risks for individuals, as well as organisational and societal costs. The success of work stress interventions depends on proper implementation. Failure to take into account the needs of employees and supervisors can hinder intervention implementation. This study aimed to explore employee and supervisor needs regarding organisational work stress prevention. METHODS: Semi-structured telephone interviews were conducted with employees (n = 7) and supervisors (n = 8) from different sectors, such as the finance, health care, and services industry...
May 21, 2018: BMC Public Health
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