Branislav Kollar, Andrey Shubin, Thiago J Borges, Sotirios Tasigiorgos, Thet Su Win, Christine G Lian, Simon T Dillon, Xuesong Gu, Iris Wyrobnik, George F Murphy, Bohdan Pomahac, Towia A Libermann, Leonardo V Riella
Face transplantation is a viable treatment option for carefully selected patients with devastating injuries to the face. However, acute rejection episodes occur in more than 80% of recipients in the first postoperative year. Unfortunately, neither a correlation between histological grades of rejection and anti-rejection treatment nor systemic surrogate markers of rejection in face transplantation are established in clinical routine. Therefore, we utilized next generation aptamer-based SOMAscan proteomics platform for non-invasive rejection biomarker discovery...
October 8, 2018: Scientific Reports