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analgosedation: you should be doing this

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2 papers 25 to 100 followers
By Jason Mann No BS pulmonary critical care fellow
Sandeep Devabhakthuni, Michael J Armahizer, Joseph F Dasta, Sandra L Kane-Gill
OBJECTIVE: To critically evaluate the use of analgosedation in the management of agitation in critically ill mechanically ventilated patients. DATA SOURCES: Literature was accessed through MEDLINE (1948-November 2011) and Cochrane Library (2011, issue 1) using the terms analgosedation, analgosedation, or analgesia-based sedation alone or in combination with intensive care unit or critically ill. Reference lists of related publications were also reviewed. STUDY SELECTION AND DATA EXTRACTION: All articles published in English were evaluated...
April 2012: Annals of Pharmacotherapy
Thomas Strøm, Torben Martinussen, Palle Toft
BACKGROUND: Standard treatment of critically ill patients undergoing mechanical ventilation is continuous sedation. Daily interruption of sedation has a beneficial effect, and in the general intesive care unit of Odense University Hospital, Denmark, standard practice is a protocol of no sedation. We aimed to establish whether duration of mechanical ventilation could be reduced with a protocol of no sedation versus daily interruption of sedation. METHODS: Of 428 patients assessed for eligibility, we enrolled 140 critically ill adult patients who were undergoing mechanical ventilation and were expected to need ventilation for more than 24 h...
February 6, 2010: Lancet
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