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IVUS /FFR/OCT

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262 papers 25 to 100 followers Papers relating to the use, value, and limitations of these advanced interventional techniques
By Gregory Gustafson Interventional Cardiologist
https://www.readbyqxmd.com/read/28864442/integrated-non-invasive-physiological-assessment-of-coronary-circulatory-function-and-impact-on-cardiovascular-mortality-in-patients-with-stable-coronary-artery-disease
#1
Ankur Gupta, Viviany R Taqueti, Tim P van de Hoef, Navkaranbir S Bajaj, Paco E Bravo, Venkatesh L Murthy, Michael T Osborne, Sara B Seidelmann, Tomas S Vita, Courtney F Bibbo, Meagan Harrington, Jon Hainer, Ornella Rimoldi, Sharmila Dorbala, Deepak L Bhatt, Ron Blankstein, Paolo G Camici, Marcelo F Di Carli
Background -It is suggested that the integration of maximal myocardial blood flow (MBF) and coronary flow reserve (CFR), termed coronary flow capacity, allows comprehensive evaluation of patients with known or suspected stable coronary artery disease. As management decisions are predicated on clinical risk, we sought to determine the independent and integrated value of maximal MBF and CFR for predicting cardiovascular death. Methods -MBF and CFR were quantified in 4,029 consecutive patients (median age 66 years, 50...
September 1, 2017: Circulation
https://www.readbyqxmd.com/read/28454806/assessing-micro-vascular-resistances-via-imr-to-predict-outcome-in-stemi-patients-with-multivessel-disease-undergoing-primary-pci-amicro-rationale-and-design-of-a-prospective-multicenter-clinical-trial
#2
MULTICENTER STUDY
Massimo Fineschi, Edoardo Verna, Giuseppe Mezzapelle, Davide Bartolini, Giovanni Turiano, Antonio Manari, Katia Lucarelli, Lucia Uguccioni, Alessandra Repetto, Giuseppe Tarantini
BACKGROUND: In STEMI patients treated with primary percutaneous coronary angioplasty (PPCI) the evaluation of coronary microcirculatory resistance index (IMR) predict the extent of microvascular damage and left ventricular (LV) remodeling. However, the impact of IMR on the clinical outcome after PPCI in patients with multivessel disease (MVD) remains unsettled. AIM: We designed a prospective multicenter controlled clinical trial to evaluate the prognostic value of IMR in terms of clinical outcome and left ventricular remodeling in STEMI patients with MVD undergoing PPCI...
May 2017: American Heart Journal
https://www.readbyqxmd.com/read/28454829/design-and-rationale-of-the-compare-acute-trial-fractional-flow-reserve-guided-primary-multivessel-percutaneous-coronary-intervention-to-improve-guideline-indexed-actual-standard-of-care-for-treatment-of-st-elevation-myocardial-infarction-in-patients-with-multivessel
#3
RANDOMIZED CONTROLLED TRIAL
Pieter C Smits, Amira Assaf, Gert Richardt, Elmir Omerovic, Mohamed Abdel-Wahab, Franz-Joseph Neumann
What the best strategy is for nonculprit lesions in ST-elevation myocardial infarction (STEMI) patients presenting with multivessel disease remains a clinical dilemma. Based on recent clinical studies suggesting that complete revascularization in the acute phase is beneficial, the European Society of Cardiology and American College of Cardiology/American Heart Association guidelines have been recently changed from class 3 discouragement to a class 2B recommendation concerning the treatment of the nonculprit lesions in the acute index procedure...
April 2017: American Heart Journal
https://www.readbyqxmd.com/read/28456699/cutoff-value-and-long-term-prediction-of%C3%A2-clinical-events-by-ffr-measured-immediately-after-implantation-of-a-drug-eluting-stent-in-patients-with-coronary-artery-disease-1-to-3-year-results-from-the-dkcrush-vii-registry-study
#4
Sui-Ji Li, Zhen Ge, Jing Kan, Jun-Jie Zhang, Fei Ye, Tak W Kwan, Teguh Santoso, Song Yang, Imad Sheiban, Xue-Song Qian, Nai-Liang Tian, Tanveer S Rab, Ling Tao, Shao-Liang Chen
OBJECTIVES: This study aimed to investigate the cutoff of post-drug-eluting stent (DES) fractional flow reserve (FFR) for prediction of 1- to 3-year target vessel failure (TVF). BACKGROUND: FFR immediately after a DES implantation correlates with clinical events. However, the cutoff of post-DES FFR for predicting long-term clinical events remains understudied. METHODS: Between May 2012 and September 2013, a total of 1,476 patients who had FFR <0...
May 22, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28475383/fractional-flow-reserve-in-2017-current-data-and-everyday-practice
#5
REVIEW
J J Coughlan, Colin MacDonnell, Samer Arnous, Thomas J Kiernan
Fractional flow reserve (FFR) is an objective physiological index utilized in coronary angiography. It expresses the blood flow in the presence of a coronary artery stenosis as a fraction of the normal blood flow and gives information regarding the functional significance of the lesion. FFR guided percutaneous coronary intervention (PCI) has been shown to be superior to angiography guided PCI in several trials and registries. In addition, it appears that the use of FFR may also be preferable from an economic perspective...
June 2017: Expert Review of Cardiovascular Therapy
https://www.readbyqxmd.com/read/28483203/correlation-between-angiographic-and-physiologic-evaluation-of-coronary-artery-narrowings-in-patients-with-aortic-valve-stenosis
#6
MULTICENTER STUDY
Giuseppe Di Gioia, Roberto Scarsini, Teresa Strisciuglio, Chiara De Biase, Carlo Zivelonghi, Danilo Franco, Bernard De Bruyne, Flavio Ribichini, Emanuele Barbato
We aimed to assess the correlation between angiographic and physiologic evaluation of coronary lesions in aortic stenosis (AS) patients presenting with intermediate coronary stenoses at the angiography. From 2002 to 2010, we included 163 patients from 2 centers with both AS and coronary artery disease (CAD), matched by age and gender with 163 contemporary patients with CAD alone. With both quantitative coronary angiography and fractional flow reserve (FFR), we assessed 259 coronary stenoses in the AS + CAD group, and 256 in the CAD alone group...
July 1, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28457806/detection-of-spontaneous-coronary-artery-spasm-with-optical-coherence-tomography-in-a-patient-with-acute-coronary-syndrome
#7
HanyTawfik Fathelbab, Santiago Jesús Camacho Freire, Javier León Jiménez, Rosa Cardenal Piris, Antonio Enrique Gómez Menchero, Jessica Roa Garrido, José Francisco Díaz Fernández
We present 2 illustrative cases of acute coronary syndrome and spontaneous coronary artery spasm evaluated by optical coherence tomography. Different spasm patterns were showed by optical coherence tomography (OCT), according to whether there were underlying atherosclerotic plaques or not.
September 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28420802/clinical-decision-making-for-the-hemodynamic-gray-zone-ffr-0-75-0-80-and-long-term-outcomes
#8
Shiv Kumar Agarwal, Srikanth Kasula, Mohan M Edupuganti, Sameer Raina, Fnu Shailesh, Ahmed Almomani, Jason J Payne, Naga V Pothineni, Barry F Uretsky, Abdul Hakeem
BACKGROUND: Fractional flow reserve (FFR) value between 0.75 and 0.80 is considered the "gray zone" and outcomes data relative to treatment strategy (revascularization vs medical therapy alone [deferral]) are limited for this group. METHODS AND RESULTS: A total of 238 patients (64.3 ± 8.6 years; 97% male; 45% diabetic) with gray-zone FFR were followed for the primary endpoint of major adverse cardiovascular event (MACE), defined as a composite of death, myocardial infarction (MI), and target-vessel revascularization...
April 15, 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/27822931/clinical-outcomes-in-patients-with-deferred-coronary-lesions-according-to-disease-severity-assessed-by-fractional-flow-reserve
#9
Ki Bum Won, Chang Wook Nam, Yun Kyeong Cho, Hyuck Jun Yoon, Hyoung Seob Park, Hyungseop Kim, Seongwook Han, Seung Ho Hur, Yoon Nyun Kim, Sang Hyun Park, Jung Kyu Han, Bon Kwon Koo, Hyo Soo Kim, Joon Hyung Doh, Sung Yun Lee, Hyoung Mo Yang, Hong Seok Lim, Myeong Ho Yoon, Seung Jea Tahk, Kwon Bae Kim
Data on the clinical outcomes in deferred coronary lesions according to functional severity have been limited. This study evaluated the clinical outcomes of deferred lesions according to fractional flow reserve (FFR) grade using Korean FFR registry data. Among 1,294 patients and 1,628 lesions in Korean FFR registry, 665 patients with 781 deferred lesions were included in this study. All participants were consecutively categorized into 4 groups according to FFR; group 1: ≥ 0.96 (n = 56), group 2: 0.86-0.95 (n = 330), group 3: 0...
December 2016: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/27866677/pressure-drop-and-arterial-compliance-two-arterial-parameters-in-one-measurement
#10
Oren M Rotman, Uri Zaretsky, Avraham Shitzer, Shmuel Einav
Coronary artery pressure-drop and distensibility (compliance) are two major, seemingly unrelated, parameters in the cardiovascular clinical setting, which are indicative of coronary arteries patency and atherosclerosis severity. While pressure drop is related to flow, and therefore serves as a functional indicator of a stenosis severity, the arterial distensibility is indicative of the arterial stiffness, and hence the arterial wall composition. In the present study, we hypothesized that local pressure drops are dependent on the arterial distensibility, and hence can provide information on both indices...
January 4, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/27872119/efficacy-of-intravenous-nicorandil-for-fractional-flow-reserve-assessment-study-protocol-for-a-crossover-randomised-trial
#11
Takeshi Nishi, Hideki Kitahara, Yoshihide Fujimoto, Takashi Nakayama, Kazumasa Sugimoto, Kengo Nagashima, Hideki Hanaoka, Yoshio Kobayashi
INTRODUCTION: Nicorandil has vasodilatory effects on both the epicardial coronary arteries and the coronary microvasculature, thereby increasing coronary blood flow. Intravenous administration of nicorandil can be applicable for fractional flow reserve (FFR) measurement as a hyperaemic agent and a possible alternative to adenosine. However, the effectiveness of intravenous nicorandil infusion for FFR measurement is largely unclear. METHODS AND ANALYSIS: This crossover randomised study is being performed to investigate the efficacy of intravenous administration of nicorandil for FFR measurement...
November 21, 2016: BMJ Open
https://www.readbyqxmd.com/read/27884241/a-prospective-natural-history-study-of%C3%A2-coronary-atherosclerosis-using-fractional-flow-reserve
#12
RANDOMIZED CONTROLLED TRIAL
Emanuele Barbato, Gabor G Toth, Nils P Johnson, Nico H J Pijls, William F Fearon, Pim A L Tonino, Nick Curzen, Zsolt Piroth, Gilles Rioufol, Peter Jüni, Bernard De Bruyne
BACKGROUND: In patients with coronary artery disease, clinical outcome depends on the extent of reversible myocardial ischemia. Whether the outcome also depends on the severity of the stenosis as determined by fractional flow reserve (FFR) remains unknown. OBJECTIVES: This study sought to investigate the relationship between FFR values and vessel-related clinical outcome. METHODS: We prospectively studied major adverse cardiovascular events (MACE) at 2 years in 607 patients in whom all stenoses were assessed by FFR and who were treated with medical therapy alone...
November 29, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27906702/diagnostic-accuracy-of-intraluminal-blood-speckle-intensity-on-intravascular-ultrasound-for-physiological-assessment-of-coronary-artery-stenosis
#13
COMPARATIVE STUDY
Yuichi Saito, Hideki Kitahara, Takashi Nakayama, Yoshihide Fujimoto, Yoshio Kobayashi
OBJECTIVES: The difference in intraluminal intensity of blood speckle (IBS) on integrated backscatter intravascular ultrasound (IVUS) across the coronary stenosis was reportedly correlated with fractional flow reserve (FFR) in the left descending coronary artery. The aim of this study was to investigate the novel physiological assessment using IVUS in all coronary arteries. PATIENTS AND METHODS: Fifty-four patients with 57 coronary lesions underwent both FFR and IVUS...
March 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/27910297/successful-retrieval-of-an-entrapped-and-uncoiled-ffr-guidewire-using-balloon-support
#14
Marco Caruso, Angelo Quagliana, Massimo Benedetto, Salvatore Asciutto, Giuseppe Cirrincione
No abstract text is available yet for this article.
February 2017: Minerva Cardioangiologica
https://www.readbyqxmd.com/read/27958692/diagnostic-accuracy-of-intravascular-ultrasound-derived-minimal-lumen-area-compared-with-fractional-flow-reserve-a-literature-review
#15
Joao P Lopes, Michelle K Jordan, Hiram Bezerra, Marco A Costa, Guilherme Attizzani
INTRODUCTION: The use of fractional flow reserve (FFR) as the gold standard for functional assessment of intermediate coronary stenosis has been well documented. Intracoronary imaging techniques such as intravascular ultrasound (IVUS) have been used for additional coronary lesion resolution and some of its anatomic parameters have been studied as having possible correlation with FFR, particularly IVUS minimal lumen area (MLA). We performed a comprehensive review of the available literature in the area...
December 13, 2016: Minerva Cardioangiologica
https://www.readbyqxmd.com/read/27969878/tct-515-prognostic-implications-of-instantaneous-wave-free-ratio-ifr-and-resting-distal-to-aortic-pressure-ratio-pd-pa-compared-with-fractional-flow-reserve-ffr-a-10-year-follow-up-study-after-deferral-of-revascularization
#16
Tim van de Hoef, Gilbert Wijntjens, Martijn Meuwissen, Mauro Echavarria Pinto, Martijn van Lavieren, Karel Koch, Steven Chamuleau, Michiel Voskuil, Robert de Winter, Jan Tijssen, Jan Piek
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27973333/reliability-of-physiological-assessment-of-coronary-stenosis-severity-using-intracoronary-pressure-techniques-a-comprehensive-analysis-from-a-large-cohort-of-consecutive-intermediate-coronary-lesions
#17
Fernando Rivero, Javier Cuesta, Teresa Bastante, Amparo Benedicto, Cristina Fernández-Pérez, Paula Antuña, Marcos García-Guimaraes, Fernando Alfonso
AIM: We sought to assess the reliability of the most frequently used intracoronary physiologic indexes (including intravenous adenosine-FFR [IV- FFR], intracoronary low-dose-adenosine FFR [IC-LD-FFR], intracoronary high- dose-adenosine FFR [IC-HD-FFR], Pd/Pa and iFR). We also sought to analyze factors affecting their reproducibility in a real world patient population. METHODS AND RESULTS: A total of 91 lesions in 86 consecutive patients were included. Measurements of all physiological indexes were repeated within a systematic standardized prospective protocol...
December 15, 2016: EuroIntervention
https://www.readbyqxmd.com/read/27979031/clinical-value-of-post-percutaneous-coronary-intervention-fractional-flow-reserve-value-a-systematic-review-and-meta-analysis
#18
REVIEW
Goran Rimac, William F Fearon, Bernard De Bruyne, Fumiaki Ikeno, Hitoshi Matsuo, Zsolt Piroth, Olivier Costerousse, Olivier F Bertrand
BACKGROUND: Fractional flow reserve (FFR) prior to percutaneous coronary intervention (PCI) is useful to guide treatment. Whether post-PCI FFR assessment might have clinical impact is controversial. The aim of this study is to evaluate the range of post-PCI FFR values and analyze the relationship between post-PCI FFR and clinical outcomes. METHODS: We systematically searched the PubMed, EMBASE, and Cochrane Library databases with cross-referencing of articles reporting post-PCI FFR and correlating post-PCI FFR values and clinical outcomes...
January 2017: American Heart Journal
https://www.readbyqxmd.com/read/27982159/comparative-study-between-perfusion-changes-and-positive-findings-on-coronary-flow-reserve
#19
COMPARATIVE STUDY
Costantino Roberto Frack Costantini, Jose Antonio Ramires, Costantino Ortiz Costantini, Marcos Antonio Denk, Sergio Gustavo Tarbine, Marcelo de Freitas Santos, Daniel Aníbal Zanuttini, Carmen Weigert Silveira, Admar Moraes de Souza, Rafael Michel de Macedo
BACKGROUND: Functional assessment of coronary artery obstruction is used in cardiology practice to correlate anatomic obstructions with flow decrease. Among such assessments, the study of the coronary fractional flow reserve (FFR) has become the most widely used. OBJECTIVE: To evaluate the correlation between FFR and findings of ischemia obtained by noninvasive methods including stress echocardiography and nuclear medicine and the presence of critical coronary artery obstruction...
January 2017: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/28025191/fractional-flow-reserve-to-guide-and-to-assess-coronary-artery-bypass-grafting
#20
Mariano Pellicano, Bernard De Bruyne, Gabor G Toth, Filip Casselman, William Wijns, Emanuele Barbato
The aim of this review is to highlight the role of invasive functional evaluation in patients in whom coronary artery bypass graft (CABG) is indicated, and to examine the clinical evidence available in favour of fractional flow reserve (FFR) adoption in these patients, outline appropriate use, as well as point out potential pitfalls. FFR after CABG will also be reviewed, highlighting its correct interpretation and adoption when applied to both native coronary arteries and bypass grafts. Practice European guidelines support the use of FFR to complement coronary angiography with the highest degree of recommendation (Class IA) for the assessment of coronary stenosis before undertaking myocardial revascularization when previous non-invasive functional evaluation is unavailable or not conclusive...
July 1, 2017: European Heart Journal
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