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Polycystic Ovarian Syndrome

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5 papers 25 to 100 followers
By Ehud Ur Professor and Head, Endocrinology, UBC, Vancouver
Eleni Magdalini Kyritsi, George K Dimitriadis, Ioannis Kyrou, Gregory Kaltsas, Harpal S Randeva
Polycystic ovarian syndrome (PCOS) is a heterogenous disorder associated with clinical, endocrine and ultrasonographic features that can also be encountered in a number of other diseases. It has traditionally been suggested that prolactin excess, enzymatic steroidogenic abnormalities and thyroid disorders need to be excluded before a diagnosis of PCOS is made. However, there is paucity of data regarding the prevalence of PCOS phenotype in some of these disorders, whereas other endocrine diseases that exhibit PCOS-like features may elude diagnosis and proper management if not considered...
September 24, 2016: Clinical Endocrinology
Andrea Dunaif
CONTEXT: Polycystic ovary syndrome (PCOS) is a common complex genetic disease. It is characterized by hyperandrogenism, gonadotropin secretory changes, polycystic ovarian morphology, and insulin resistance. The etiology of PCOS remains unknown, but modern genetic approaches, such as genome-wide association studies (GWAS), Mendelian randomization, and next-generation sequencing, promise to identify the pathways that are primarily disrupted. EVIDENCE ACQUISITION: The literature on PCOS, including the author's research, is discussed...
March 2016: Journal of Clinical Endocrinology and Metabolism
Brian G Keevil
No abstract text is available yet for this article.
March 2014: Journal of Clinical Endocrinology and Metabolism
Hamidreza Mani, Neelam Potdar, Helena Gleeson
Polycystic ovary syndrome (PCOS), or the potential diagnosis of PCOS, is one of the most common reasons for adolescent girls to present to endocrinology clinics. A diagnosis of PCOS has the potential to affect the young person, not only physically, but psychologically and socially. It is important we have the knowledge, skills and attitudes to work effectively with young people to address their concerns and meet their information needs. Successful engagement and management of adolescents with PCOS may have implications in adult life...
November 2014: Clinical Endocrinology
Jacqueline A Boyle, Helena J Teede
No abstract text is available yet for this article.
August 5, 2014: CMAJ: Canadian Medical Association Journal, Journal de L'Association Medicale Canadienne
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