Anna Galyean, Thomas J Garite, Kimberly Maurel, Diana Abril, Charles D Adair, Paul Browne, C Andrew Combs, Helen How, Brian K Iriye, Michelle Kominiarek, George Lu, David Luthy, Hugh Miller, Michael Nageotte, Tulin Ozcan, Manuel Porto, Mildred Ramirez, Shirley Sawai, Yoram Sorokin
OBJECTIVE: The decision of whether to retain or remove a previously placed cervical cerclage in women who subsequently rupture fetal membranes in a premature gestation is controversial and all studies to date are retrospective. We performed a multicenter randomized controlled trial of removal vs retention of cerclage in these patients to determine whether leaving the cerclage in place prolonged gestation and/or increased the risk of maternal or fetal infection. STUDY DESIGN: A prospective randomized multicenter trial of 27 hospitals was performed...
October 2014: American Journal of Obstetrics and Gynecology