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Contrast Induced Nephropathy

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121 papers 100 to 500 followers
By Isabel Acosta-Ochoa Nephrology senior staff. Valladolid. Spain
https://www.readbyqxmd.com/read/29976375/bilateral-sustained-nephrograms-after-parenteral-administration-of-iodinated-contrast-material-a-potential-biomarker-for-acute-kidney-injury-dialysis-and-mortality
#1
Jennifer S McDonald, Erik M Steckler, Robert J McDonald, Richard W Katzberg, Eric E Williamson, Joseph G Cernigliaro, Abdurrahman M Hamadah, Kamel Gharaibeh, David F Kallmes, Nelson Leung
OBJECTIVE: To determine whether persistent bilateral global nephrograms are associated with acute kidney injury (AKI), dialysis, and mortality. PATIENTS AND METHODS: All patients who underwent (1) contrast-enhanced computed tomography (CT) or cardiac catheterization with iohexol between January 1, 2000, and December 31, 2014, and (2) noncontrast abdominal CT in the subsequent 24±6 hours were identified. Patients without preprocedure and postprocedure creatinine measurements or who received additional contrast material were excluded...
July 2018: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/29977584/gadolinium-based-contrast-agents-in-kidney-disease-a-comprehensive-review-and-clinical-practice-guideline-issued-by-the-canadian-association-of-radiologists
#2
Nicola Schieda, Jason I Blaichman, Andreu F Costa, Rafael Glikstein, Casey Hurrell, Matthew James, Pejman Jabehdar Maralani, Wael Shabana, An Tang, Anne Tsampalieros, Christian B van der Pol, Swapnil Hiremath
Purpose of review: Use of gadolinium-based contrast agents (GBCA) in renal impairment is controversial, with physician and patient apprehension in acute kidney injury (AKI), chronic kidney disease (CKD), and dialysis because of concerns regarding nephrogenic systemic fibrosis (NSF). The position that GBCA are absolutely contraindicated in AKI, category G4 and G5 CKD (estimated glomerular filtration rate [eGFR] < 30 mL/min/1.73 m2 ), and dialysis-dependent patients is outdated and may limit access to clinically necessary contrast-enhanced magnetic resonance imaging (MRI) examinations...
2018: Canadian Journal of Kidney Health and Disease
https://www.readbyqxmd.com/read/29932411/contrast-associated-nephropathy-does-the-route-of-administration-matter
#3
Catherine Mao, Bobby Chacko
Contrast-associated nephropathy (CAN) is an extensively studied but equally controversial sequela of intravascular contrast use. Despite this, there is still significant debate about its definition and thus incidence, the impact of route of contrast administration, and ultimately, what constitutes appropriate clinical practice in light of risks. While guidelines cannot replace clinical judgment, without consensus either enthusiastic withholding of contrast from necessary procedures or its administration despite increased risk may be deleterious to patient outcomes...
June 22, 2018: Clinical Nephrology
https://www.readbyqxmd.com/read/29929610/bioimpedance-guided-hydration-for-the-prevention-of-contrast-induced-kidney-injury-the-hydra-study
#4
Mauro Maioli, Anna Toso, Mario Leoncini, Nicola Musilli, Gabriele Grippo, Claudio Ronco, Peter A McCullough, Francesco Bellandi
BACKGROUND: Intravascular volume expansion plays a major role in the prevention of contrast-induced acute kidney injury (CI-AKI). Recommended standard amounts of fluid infusion before procedures do not produce homogeneous responses in subjects with different initial hydration status. OBJECTIVES: The goal of this study was to compare the effect of standard and double intravenous (IV) infusion volumes in patients with low body fluid level, assessed by using bioimpedance vector analysis (BIVA), on the incidence of CI-AKI after elective coronary angiographic procedures...
June 26, 2018: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/25780349/incidence-and-outcome-of-contrast-associated-acute-kidney-injury-assessed-with-risk-injury-failure-loss-and-end-stage-kidney-disease-rifle-criteria-in-critically-ill-patients-of-medical-and-surgical-intensive-care-units-a-retrospective-study
#5
Myoung Hwa Kim, Shin Ok Koh, Eun Jung Kim, Jin Sun Cho, Sung-Won Na
BACKGROUND: Contrast medium used for radiologic tests can decrease renal function. However there have been few studies on contrast-associated acute kidney injury in intensive care unit (ICU) patients. The objective of this study was to evaluate the incidence, characteristics, and outcome of contrast-associated acute kidney injury (CA-AKI) patients using the Risk, Injury, Failure, Loss, and End-stage kidney disease (RIFLE) criteria in critically ill patients in the ICU. METHODS: We conducted a retrospective study of adult patients who underwent contrast-enhanced radiologic tests from January 2011 to December 2012 in a 30-bed medical ICU and a 24-bed surgical ICU...
2015: BMC Anesthesiology
https://www.readbyqxmd.com/read/29868731/pro-contrast-induced-nephropathy-should-we-try-to-avoid-contrast-media-in-patients-with-chronic-kidney-disease
#6
Martin Windpessl, Andreas Kronbichler
The administration of iodinated contrast medium (CM) has immediate negative impact on multiple levels of the nephron, including vasoconstriction, an increase in apoptotic pathways and oxidative stress. Therefore, contrast-induced acute kidney injury (CI-AKI) remains an important cause of sudden impairment of renal function. Far from being just a transient phenomenon, CI-AKI has consistently been shown to be associated with adverse outcomes. The phenomenon of chronic kidney disease (CKD) following AKI might explain why this entity portends a poor prognosis in the long run...
June 3, 2018: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/29868835/con-contrast-induced-nephropathy-should-we-try-to-avoid-contrast-media-in-patients-with-chronic-kidney-disease
#7
Michael J Ewing, John F Eidt
The incidence of acute kidney injury (AKI) attributed to iodinated contrast has been over-estimated and this has led clinicians to withhold potentially life-saving diagnostic and therapeutic interventions. There is mounting evidence that iodinated contrast plays only a minor role in the development of AKI in comparison with more significant risk factors such as pre-existing renal dysfunction, hemodynamic instability and exposure to nephrotoxic drugs. We will present data which challenge the dogma of avoiding iodinated contrast in patients with reduced renal function...
June 3, 2018: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/29761901/the-fear-for-contrast-induced-nephropathy-in-kidney-transplant-recipients-time-for-a-paradigm-shift
#8
LETTER
Stan Benjamens, Derya Yakar, Riemer H J A Slart, Jan-Stephan F Sanders, Robert A Pol
No abstract text is available yet for this article.
May 15, 2018: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/29731093/graft-contrast-induced-nephropathy-caused-by-prerenal-transplant-computed-tomography-a-case-report
#9
S D Hwang, K-M Park, S W Lee, J-Y Han, M-J Kim, J H Song
BACKGROUND: We report a case of posttransplant contrast-induced nephropathy (CIN) that occurred after performing computed tomography (CT) scanning for pretransplant cardiac and vascular evaluation. CASE PRESENTATION: The patient had an 8-year history of hemodialysis and was admitted to the hospital for a kidney transplant from a deceased donor. Cardiac CT imaging and 3-dimensional low-extremity CT angiography were performed to confirm the patient's cardiac and iliac artery function...
May 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29674341/contrast-induced-acute-kidney-injury-in-the-preserve-trial-lessons-learned
#10
Edward D Siew, Kathleen D Liu
No abstract text is available yet for this article.
June 7, 2018: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/29687326/are-iso-osmolar-as-compared-to-low-osmolar-contrast-media-cost-effective-in-patients-undergoing-cardiac-catheterization-an-economic-analysis
#11
Swapnil Hiremath, Ayub Akbari, George A Wells, Benjamin J W Chow
PURPOSE: Contrast-induced acute kidney injury is a prominent complication following cardiac catheterization, though the risk has progressively decreased in recent times with appropriate risk stratification and use of safer contrast agents. Despite data supporting further lowering of risk with the iso-osmolar agent, iodixanol, uptake has lagged, perhaps due to increased upfront cost of this agent. We undertook an economic analysis to estimate the cost-effectiveness of a strategy utilizing iodixanol compared to using a low-osmolar contrast agent...
April 23, 2018: International Urology and Nephrology
https://www.readbyqxmd.com/read/29672267/point-of-care-creatinine-testing-for-kidney-function-measurement-prior-to-contrast-enhanced-diagnostic-imaging-evaluation-of-the-performance-of-three-systems-for-clinical-utility
#12
Beverly Snaith, Martine A Harris, Bethany Shinkins, Marieke Jordaan, Michael Messenger, Andrew Lewington
BACKGROUND: Acute kidney injury (AKI) can occur rarely in patients exposed to iodinated contrast and result in contrast-induced AKI (CI-AKI). A key risk factor is the presence of preexisting chronic kidney disease (CKD); therefore, it is important to assess patient risk and obtain kidney function measurement prior to administration. Point-of-care (PoC) testing provides an alternative strategy but there remains uncertainty, with respect to diagnostic accuracy and clinical utility. METHODS: A device study compared three PoC analysers (Nova StatSensor, Abbott i-STAT and Radiometer ABL800 FLEX) with a reference laboratory standard (Roche Cobas 8000 series, enzymatic creatinine)...
April 19, 2018: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/29657720/promising-novel-therapy-with-hydrogen-gas-for-emergency-and-critical-care-medicine
#13
REVIEW
Motoaki Sano, Masaru Suzuki, Koichiro Homma, Kei Hayashida, Tomoyoshi Tamura, Tadashi Matsuoka, Yoshinori Katsumata, Shuko Onuki, Junichi Sasaki
It has been reported that hydrogen gas exerts a therapeutic effect in a wide range of disease conditions, from acute illness such as ischemia-reperfusion injury, shock, and damage healing to chronic illness such as metabolic syndrome, rheumatoid arthritis, and neurodegenerative diseases. Antioxidant and anti-inflammatory properties of hydrogen gas have been proposed, but the molecular target of hydrogen gas has not been identified. We established the Center for Molecular Hydrogen Medicine to promote non-clinical and clinical research on the medical use of hydrogen gas through industry-university collaboration and to obtain regulatory approval of hydrogen gas and hydrogen medical devices (http://www...
April 2018: Acute Medicine & Surgery
https://www.readbyqxmd.com/read/29633091/vitamins-for-prevention-of-contrast-induced-acute-kidney-injury-a-systematic-review-and-trial-sequential-analysis
#14
REVIEW
Yongxing Xu, Xinming Zheng, Boran Liang, Jianjun Gao, Zhaoyan Gu
BACKGROUND: To date, universally accepted preventive measures for contrast-induced acute kidney injury (CI-AKI) do not exist, and they warrant further research. OBJECTIVE: The purpose of this study was to evaluate the efficacy of vitamins, including vitamin C and E, for prevention of CI-AKI. METHODS: We electronically searched the MEDLINE, EMBASE, and Cochrane databases. The outcome of interest was the incidence of CI-AKI. RESULTS: A total of 19 studies were included in this meta-analysis...
April 9, 2018: American Journal of Cardiovascular Drugs: Drugs, Devices, and Other Interventions
https://www.readbyqxmd.com/read/29513790/urinary-semaphorin-3a-as-an-early-biomarker-to-predict-contrast-induced-acute-kidney-injury-in-patients-undergoing-percutaneous-coronary-intervention
#15
Li Ning, Zhiguo Li, Dianjun Wei, Haiyan Chen, Chao Yang, Dawei Wu, Yanchun Wang, Jingwei Zhang
Contrast-induced acute kidney injury (CI-AKI) is a serious complication of diagnostic coronary angiograph and percutaneous coronary intervention (PCI). However, the exact pathophysiological mechanisms underlying CI-AKI development are largely unknown. The present study examined whether urinary semaphorin 3A levels predict the development of CI-AKI in patients undergoing PCI. This study enrolled 168 patients with stable angina undergoing elective PCI. Serial urine samples, obtained at baseline and 2, 6, 12, 24, 36, and 48 h post-PCI were analyzed by semaphorin 3A and neutrophil gelatinase-associated lipocalin (NGAL) ELISA kit...
March 1, 2018: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/29475535/zero-contrast-percutaneous-coronary-intervention-guided-by-dextran-based-optical-coherence-tomography
#16
Lorenzo Azzalini, Satoru Mitomo, Daisuke Hachinohe, Damiano Regazzoli, Antonio Colombo
Individuals with advanced chronic kidney disease (CKD) and coronary artery disease are often denied percutaneous coronary intervention (PCI) because of an aversion to the risk of contrast-induced nephropathy. We present the case of a 76-year-old man with stage 4 CKD requiring coronary revascularization. Zero-contrast PCI was successfully performed using dextran-based optical coherence tomography (OCT) guidance. Our report suggests the feasibility of dextran-based, OCT-guided, zero-contrast PCI in patients with advanced CKD...
March 2018: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/29463106/association-of-preprocedural-hyperglycemia-with-contrast-induced-acute-kidney-injury-and-poor-outcomes-after-emergency-percutaneous-coronary-intervention
#17
Kai-Yang Lin, Xiu-Ling Shang, Yan-Song Guo, Peng-Li Zhu, Zhi-Yong Wu, Hui Jiang, Jing-Ming Ruan, Wei-Ping Zheng, Zhe-Bin You, Chun-Jin Lin
We investigated whether preprocedural hyperglycemia was associated with contrast-induced acute kidney injury (CI-AKI) and long-term outcomes in patients with acute coronary syndrome (ACS) who underwent emergency percutaneous coronary intervention (PCI). Patients (n = 558) with ACS who underwent emergency PCI were consecutively enrolled. Preprocedural hyperglycemia was defined as glucose levels >198 mg/dL (11 mmol/L). The primary outcome was CI-AKI (≥0.3 mg/dL absolute or ≥50% relative serum creatinine increase 48 hours after contrast medium exposure)...
January 1, 2018: Angiology
https://www.readbyqxmd.com/read/29456202/contrast-induced-nephropathy-pathophysiology-risk-factors-and-prevention
#18
REVIEW
Mohammad A Hossain, Eric Costanzo, James Cosentino, Chirag Patel, Huzaif Qaisar, Vikas Singh, Taimoor Khan, Jennifer S Cheng, Arif Asif, Tushar J Vachharajani
Contrast-induced acute kidney injury is a common iatrogenic complication associated with increased health resource utilization and adverse outcomes, including short- and long-term mortality and accelerated progression of preexisting renal insufficiency. The incidence of contrast-induced nephropathy (CIN) has been reported to range from 0% to 24%. This wide range reported by the studies is due to differences in definition, background risk factors, type and dose of contrast medium used, and the frequency of other coexisting potential causes of acute renal failure...
January 2018: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/29443675/prevention-of-contrast-associated-acute-kidney-injury
#19
EDITORIAL
Mitchell H Rosner
No abstract text is available yet for this article.
February 15, 2018: New England Journal of Medicine
https://www.readbyqxmd.com/read/29426991/post-contrast-acute-kidney-injury-part-1-definition-clinical-features-incidence-role-of-contrast-medium-and-risk-factors-recommendations-for-updated-esur-contrast-medium-safety-committee-guidelines
#20
Aart J van der Molen, Peter Reimer, Ilona A Dekkers, Georg Bongartz, Marie-France Bellin, Michele Bertolotto, Olivier Clement, Gertraud Heinz-Peer, Fulvio Stacul, Judith A W Webb, Henrik S Thomsen
PURPOSE: The Contrast Media Safety Committee (CMSC) of the European Society of Urogenital Radiology (ESUR) has updated its 2011 guidelines on the prevention of post-contrast acute kidney injury (PC-AKI). The results of the literature review and the recommendations based on it, which were used to prepare the new guidelines, are presented in two papers. AREAS COVERED IN PART 1: Topics reviewed include the terminology used, the best way to measure eGFR, the definition of PC-AKI, and the risk factors for PC-AKI, including whether the risk with intravenous and intra-arterial contrast medium differs...
July 2018: European Radiology
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