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Essential Surgical Knowledge

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2170 papers 1000+ followers Papers from the recent literature which are of interest to residents and practicing surgeons
https://www.readbyqxmd.com/read/30098412/appraising-the-uptake-and-use-of-the-ideal-framework-and-recommendations-a-review-of-the-literature
#1
REVIEW
Asha Khachane, Yiannis Philippou, Allison Hirst, Peter McCulloch
INTRODUCTION: Evaluation of new surgical innovations is complex and variably regulated, and historically the quality of surgical studies has been criticized. The IDEAL (Idea, Development, Exploration, Assessment, Long-term monitoring) Framework was established to provide a pathway for evaluating surgical innovations at each stage of their development in order to produce high quality surgical research. Since the inception of IDEAL in 2009, there has been no assessment of its use. In this review, we look at the uptake and usage of IDEAL by examining the published literature...
August 8, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/30097460/corticosteroid-therapy-for-sepsis-a-clinical-practice-guideline
#2
Francois Lamontagne, Bram Rochwerg, Lyubov Lytvyn, Gordon H Guyatt, Morten Hylander Møller, Djillali Annane, Michelle E Kho, Neill K J Adhikari, Flavia Machado, Per O Vandvik, Peter Dodek, Rebecca Leboeuf, Matthias Briel, Madiha Hashmi, Julie Camsooksai, Manu Shankar-Hari, Mahder Kinfe Baraki, Karie Fugate, Shunjie Chua, Christophe Marti, Dian Cohen, Edouard Botton, Thomas Agoritsas, Reed A C Siemieniuk
No abstract text is available yet for this article.
August 10, 2018: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/30098620/the-management-of-venous-thromboembolic-disease-new-trends-in-anticoagulant-therapy
#3
REVIEW
Andrea Obi, Thomas Wakefield
No abstract text is available yet for this article.
September 2018: Advances in Surgery
https://www.readbyqxmd.com/read/30081081/patients-undergoing-parastomal-hernia-repair-using-the-americas-hernia-society-quality-collaborative-a-prospective-cohort-study
#4
Thomas Gavigan, Thomas Stewart, Brent Matthews, Caroline Reinke
INTRO: Parastomal hernia is the most common complication after stoma creation. They can create significant morbidity and are associated with a lower quality of life. Current parastomal hernia repair techniques and outcomes are not well characterized. We aimed to describe patient characteristics, operative techniques, and outcomes of patients undergoing parastomal hernia repair. METHODS: Patients in the AHSQC ≥18 years who underwent parastomal hernia repair were identified...
August 3, 2018: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/30080701/epidemiology-of-icu-acquired-pneumonia
#5
Miquel Ferrer, Antoni Torres
PURPOSE OF REVIEW: Review of the epidemiology of ICU-acquired pneumonia, including both ventilator-associated pneumonia (VAP) and hospital-acquired pneumonia (HAP) in nonventilated ICU patients, with critical review of the most recent literature in this setting. RECENT FINDINGS: The incidence of ICU-acquired pneumonia, mainly VAP has decrease significantly in recent years possibly due to the generalized implementation of preventive bundles. However, the exact incidence of VAP is difficult to establish due to the diagnostic limitations and the methods employed to report rates...
August 2, 2018: Current Opinion in Critical Care
https://www.readbyqxmd.com/read/30078107/perioperative-risk-prediction-in-the-era-of-enhanced-recovery-a-comparison-of-possum-acpgbi-and-e-pass-scoring-systems-in-major-surgical-procedures-of-the-colorectal-surgeon
#6
Nigel M Bagnall, Edward T Pring, George Malietzis, Thanos Athanasiou, Omar D Faiz, Robin H Kennedy, John T Jenkins
PURPOSE: This study aims to determine whether traditional risk models can accurately predict morbidity and mortality in patients undergoing major surgery by colorectal surgeons within an enhanced recovery program. METHODS: One thousand three hundred eighty patients undergoing surgery performed by colorectal surgeons in a single UK hospital (2008-2013) were included. Six risk models were evaluated: (1) Physiology and Operative Severity Score for the enumeration of Mortality and Morbidity (POSSUM), (2) Portsmouth POSSUM (P-POSSUM), (3) ColoRectal (CR-POSSUM), (4) Elderly POSSUM (E-POSSUM), (5) the Association of Great Britain and Ireland (ACPGBI) score, and (6) modified Estimation of Physiologic Ability and Surgical Stress Score (E-PASS)...
August 4, 2018: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/30073665/colloids-versus-crystalloids-for-fluid-resuscitation-in-critically-ill-people
#7
REVIEW
Sharon R Lewis, Michael W Pritchard, David Jw Evans, Andrew R Butler, Phil Alderson, Andrew F Smith, Ian Roberts
BACKGROUND: Critically ill people may lose fluid because of serious conditions, infections (e.g. sepsis), trauma, or burns, and need additional fluids urgently to prevent dehydration or kidney failure. Colloid or crystalloid solutions may be used for this purpose. Crystalloids have small molecules, are cheap, easy to use, and provide immediate fluid resuscitation, but may increase oedema. Colloids have larger molecules, cost more, and may provide swifter volume expansion in the intravascular space, but may induce allergic reactions, blood clotting disorders, and kidney failure...
August 3, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29624860/hepatic-encephalopathy-diagnosis-and-management
#8
REVIEW
Piero Amodio
Hepatic encephalopathy (HE) is a peculiar kind of brain dysfunction caused by liver insufficiency and/or portal-systemic shunting. It is related to gut-derived substances. It is a relevant cause of morbidity and hospitalisation for patients with cirrhosis. The prognosis of HE is important in terms of survival and re-hospitalisation. It is related to impaired quality of life, falls and poor driving; presents a relevant burden for caregivers and health services; and may negatively impact on patient's job and income...
June 2018: Liver International: Official Journal of the International Association for the Study of the Liver
https://www.readbyqxmd.com/read/30065783/the-abdominal-wall-hernia-in-cirrhotic-patients-a-historical-challenge
#9
Giuseppe Salamone, Leo Licari, Giovanni Guercio, Sofia Campanella, Nicolò Falco, Gregorio Scerrino, Sebastiano Bonventre, Girolamo Geraci, Gianfranco Cocorullo, Gaspare Gulotta
Background: The incidence rate of abdominal wall hernia is 20-40% in cirrhotic patients. A surgical approach was originally performed only if complication signs and symptoms occurred. Several recent studies have demonstrated the usefulness of elective surgery. During recent decades, the indications for surgical timing have changed. Methods: Cirrhotic patients with abdominal hernia who underwent surgical operation for abdominal wall hernia repair at the Policlinico "Paolo Giaccone" at Palermo University Hospital between January 2010 and September 2016 were identified in a prospective database, and the data collected were retrospectively reviewed; patients' medical and surgical records were collected from charts and surgical and intensive care unit (ICU) registries...
2018: World Journal of Emergency Surgery: WJES
https://www.readbyqxmd.com/read/30067545/the-impact-of-corporate-payments-on-robotic-surgery-research-a-systematic-review
#10
Cory N Criss, Mark P MacEachern, Niki Matusko, Justin B Dimick, Melinda Maggard-Gibbons, Samir K Gadepalli
OBJECTIVE: To quantify the influence of financial conflict of interest (COI) payments on the reporting of clinical results for robotic surgery. DATA SOURCES AND STUDY SELECTION: A systematic search (Ovid MEDLINE databases) was conducted (May 2017) to identify randomized controlled trials (RCTs) and observational studies comparing the efficacy of the da Vinci robot on clinical outcomes. Financial COI data for authors (per study) were determined using open payments database...
July 31, 2018: Annals of Surgery
https://www.readbyqxmd.com/read/30037652/we-are-the-gatekeepers-or-your-residency-is-only-as-good-as-your-worst-graduate
#11
Daniel L Dent, Mohammed Al Fayyadh, Ross E Willis
No abstract text is available yet for this article.
July 20, 2018: Journal of Surgical Education
https://www.readbyqxmd.com/read/30041967/resection-for-anal-melanoma-is-there-an-optimal-approach
#12
Molly M Ford, Rondi M Kauffmann, Timothy M Geiger, M Benjamin Hopkins, Roberta L Muldoon, Alexander T Hawkins
BACKGROUND: Anal melanoma is a lethal disease, but its rarity makes understanding the behavior and effects of intervention challenging. Local resection and abdominal perineal resection are the proposed treatments for nonmetastatic disease. We hypothesize that there is no difference in overall survival between surgical therapies. METHODS: The National Cancer Database (2004-2014) was queried for adults with a diagnosis of anal melanoma who underwent curative resection...
July 2, 2018: Surgery
https://www.readbyqxmd.com/read/30046808/association-of-intraoperative-findings-with-outcomes-and-resource-use-in-children-with-complicated-appendicitis
#13
Seema P Anandalwar, Danielle B Cameron, Dionne A Graham, Patrice Melvin, Jonathan L Dunlap, Mark Kashtan, Matthew Hall, Jacqueline M Saito, Douglas C Barnhart, Brian D Kenney, Shawn J Rangel
Importance: The influence of disease severity on outcomes and use of health care resources in children with complicated appendicitis is poorly characterized. Adjustment for variation in disease severity may have implications for ensuring fair reimbursement and comparative performance reporting among hospitals. Objective: To examine the association of intraoperative findings as a measure of disease severity with complication rates and resource use in children with complicated appendicitis...
July 25, 2018: JAMA Surgery
https://www.readbyqxmd.com/read/30018476/current-clinical-management-of-gastrointestinal-stromal-tumor
#14
REVIEW
Kazuya Akahoshi, Masafumi Oya, Tadashi Koga, Yuki Shiratsuchi
Gastrointestinal stromal tumors (GISTs) are the most common malignant subepithelial lesions (SELs) of the gastrointestinal tract. They originate from the interstitial cells of Cajal located within the muscle layer and are characterized by over-expression of the tyrosine kinase receptor KIT. Pathologically, diagnosis of a GIST relies on morphology and immunohistochemistry [KIT and/or discovered on gastrointestinal stromal tumor 1 (DOG1) is generally positive]. The prognosis of this disease is associated with the tumor size and mitotic index...
July 14, 2018: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/30043994/open-or-endovascular-revascularization-in-the-treatment-of-acute-lower-limb-ischaemia
#15
O Grip, A Wanhainen, K Michaëlsson, L Lindhagen, M Björck
BACKGROUND: Consensus is lacking regarding intervention for patients with acute lower limb ischaemia (ALI). The aim was to study amputation-free survival in patients treated for ALI by either primary open or endovascular revascularization. METHODS: The Swedish Vascular Registry (Swedvasc) was combined with the Population Registry and National Patient Registry to determine follow-up on mortality and amputation rates. Revascularization techniques were compared by propensity score matching 1 : 1...
July 25, 2018: British Journal of Surgery
https://www.readbyqxmd.com/read/30039324/an-update-on-immunotherapy-for-solid-tumors-a-review
#16
REVIEW
Toan Pham, Sara Roth, Joseph Kong, Glen Guerra, Vignesh Narasimhan, Lloyd Pereira, Jayesh Desai, Alexander Heriot, Robert Ramsay
In recent years, it has been demonstrated that immunotherapy is an effective strategy for the management of solid tumors. The origins of immunotherapy can be traced back to the work of William Coley, who elicited an immune response against sarcoma by injecting patients with a mixture of dead bacteria. Significant progress has been made since, with immune markers within the tumor now being used as predictors of cancer prognosis and manipulated to improve patient survival. While surgery remains central to the management of most patients with solid malignancies, it is important that surgeons consider the different immunotherapy strategies that can be employed to manage disease...
July 23, 2018: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/30029846/incidence-and-risk-factors-for-sepsis-after-childhood-splenectomy
#17
Arin L Madenci, Lindsey B Armstrong, Nicollette K Kwon, Wei Jiang, Lindsey L Wolf, Tracey P Koehlmoos, Robert L Ricca, Christopher B Weldon, Adil H Haider, Brent R Weil
BACKGROUND: Children who have undergone splenectomy may develop impaired immunologic function and heightened risk of overwhelming postsplenectomy infection. We sought to define the long-term rate of and risk factors for postsplenectomy sepsis. METHODS: We leveraged the Military Health System Data Repository, a nationally representative claims database including >3 million children registered as dependents of members of the United States Armed Services (2005-2014)...
June 25, 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/30019405/profile-of-exhaled-breath-volatile-organic-compounds-to-diagnose-pancreatic-cancer
#18
S R Markar, B Brodie, S-T Chin, A Romano, D Spalding, G B Hanna
BACKGROUND: Pancreatic cancer has a very poor prognosis as most patients are diagnosed at an advanced stage when curative treatments are not possible. Breath volatile organic compounds (VOCs) have shown potential as novel biomarkers to detect cancer. The aim of the study was to quantify differences in exhaled breath VOCs of patients with pancreatic cancers compared with cohorts without cancer. METHODS: Patients were recruited to an initial development cohort and a second validation cohort...
July 18, 2018: British Journal of Surgery
https://www.readbyqxmd.com/read/30007406/treatment-options-for-pnet-liver-metastases-a-systematic-review
#19
REVIEW
Giuseppe Nigri, Niccolò Petrucciani, Tarek Debs, Livia Maria Mangogna, Anna Crovetto, Giovanni Moschetta, Raffaello Persechino, Paolo Aurello, Giovanni Ramacciato
BACKGROUND: Pancreatic neuroendocrine tumors (PNETs) are rare pancreatic neoplasms. About 40-80% of patients with PNET are metastatic at presentation, usually involving the liver (40-93%). Liver metastasis represents the most significant prognostic factor. The aim of this study is to present an up-to-date review of treatment options for patients with liver metastases from PNETs. METHODS: A systematic literature search was performed using the PubMed database to identify all pertinent studies published up to May 2018...
July 14, 2018: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29980848/the-state-of-the-art-on-treatment-of-crohn-s-disease
#20
REVIEW
Hai Yun Shi, Siew Chien Ng
Crohn's disease (CD) is a chronic, progressive, and destructive disease of the gastrointestinal tract. Although its incidence appears to be stable or decreasing in most countries in the North America and Europe, the incidence is rising rapidly in Asian countries. Immunomodulators and biologics are increasingly used to avoid long-term bowel damage and subsequent disability. Therapeutic drug monitoring facilitates optimizing thiopurines and anti-TNFs use. New biologic agents targeting various pathological pathways of CD are blooming in recent years, and the high cost of biologics and expiration of patents for several biologic agents have driven the utility of biosimilars for CD treatment...
July 6, 2018: Journal of Gastroenterology
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