Haruhiko Cho, Junichi Nakamura, Yoshihide Asaumi, Hiroshi Yabusaki, Masahiro Sakon, Naoki Takasu, Tatsunori Kobayashi, Taro Aoki, Osamu Shiraishi, Hirofumi Kishimoto, Souya Nunobe, Shinji Yanagisawa, Takeshi Suda, Shigeyuki Ueshima, Satoru Matono, Hiroshi Maruyama, Mitsutoshi Tatsumi, Tomoko Seya, Yutaka Tanizawa, Takaki Yoshikawa
BACKGROUND: A pathologic complete response (pCR) can sometimes be induced by intensive or long-term neoadjuvant chemotherapy (NAC). This prognostic research study based on a systematic review of the literature evaluated the impact of a pCR on the long-term survival of gastric cancer (GC) patients. METHODS: Articles were extracted from PubMed and the Japanese medical search engine "Ichu-shi," using the terms "GC," "NAC," and "pCR." Articles were selected based on the following criteria: (1) full-text case report, (2) R0 resection following NAC for locally advanced GC, and (3) pathological complete response in both the primary stomach and in the lymph nodes...
March 2015: Annals of Surgical Oncology