Use the collections feature with a free QxMD account.
Use Read by QxMD to access full text via your institution or open access sources.
Read also provides personalized recommendations to keep you up to date in your field.
Existing User
Sign InNew to Read
Sign Up#1
REVIEW
Timo Mayerhöfer, Fabian Perschinka, Michael Joannidis
Acute kidney injury (AKI) is a common problem in critically ill patients and is associated with increased morbidity and mortality. Since 2012, AKI has been defined according to the KDIGO (Kidney Disease Improving Global Outcome) guidelines. As some biomarkers are now available that can provide useful clinical information, a new definition including a new stage 1S has been proposed by an expert group of the Acute Disease Quality Initiative (ADQI). At this stage, classic AKI criteria are not yet met, but biomarkers are already positive defining subclinical AKI...
April 29, 2024: Medizinische Klinik, Intensivmedizin und Notfallmedizin
#2
JOURNAL ARTICLE
Yeong-Won Park, Donghwan Yun, Yeojin Yu, Sang Hyun Kim, Sehoon Park, Yong Chul Kim, Dong Ki Kim, Kook-Hwan Oh, Kwon Wook Joo, Yon Su Kim, Seong Geun Kim, Seung Seok Han
BACKGROUND: Intradialytic hypotension (IDH) is a critical complication related to worse outcomes in patients undergoing maintenance hemodialysis. Herein, we addressed the impact of IDH on mortality and other outcomes in patients with severe acute kidney injury (AKI) requiring intermittent hemodialysis. METHODS: We retrospectively reviewed 1,009 patients who underwent intermittent hemodialysis due to severe AKI. IDH was defined as either dialysis discontinuation due to hemodynamic instability or a decrease in systolic blood pressure (BP) of ≥30 mmHg, with or without a nadir systolic BP of <90 mmHg during the first session...
February 19, 2024: Kidney Research and Clinical Practice
#3
Jaye Platnich, Janice Y Kung, Adam S Romanovsky, Marlies Ostermann, Ron Wald, Neesh Pannu, Sean M Bagshaw
INTRODUCTION: Critical care nephrology is a subspecialty that merges critical care and nephrology in response to shared pathobiology, clinical care, and technological innovations. To date, there has been no description of the highest impact articles. Accordingly, we systematically identified high impact articles in critical care nephrology. METHODS: This was a bibliometric analysis. The search was developed by a research librarian. Web of Science was searched for articles published between January 1, 2000 and December 31, 2020...
December 5, 2023: Blood Purification
#4
JOURNAL ARTICLE
Theresa Mottes, Shina Menon, Andrea Conroy, Jennifer Jetton, Kristin Dolan, Ayse Akcan Arikan, Rajit K Basu, Stuart L Goldstein, Jordan M Symons, Rashid Alobaidi, David J Askenazi, Sean M Bagshaw, Matthew Barhight, Erin Barreto, Benan Bayrakci, O N Bignall Ray, Erica Bjornstad, Patrick Brophy, Jennifer Charlton, Rahul Chanchlani, Andrea L Conroy, Akash Deep, Prasad Devarajan, Dana Fuhrman, Katja M Gist, Stephen M Gorga, Jason H Greenberg, Denise Hasson, Emma Heydari, Arpana Iyengar, Catherine Krawczeski, Leslie Meigs, Catherine Morgan, Jolyn Morgan, Tara Neumayr, Zaccaria Ricci, David T Selewski, Danielle Soranno, Natalja Stanski, Michelle Starr, Scott M Sutherland, Jordan Symons, Marcelo Tavares, Molly Vega, Michael Zappitelli, Claudio Ronco, Ravindra L Mehta, John Kellum, Marlies Ostermann
BACKGROUND: Acute kidney injury (AKI) is independently associated with increased morbidity and mortality across the life course, yet care for AKI remains mostly supportive. Raising awareness of this life-threatening clinical syndrome through education and advocacy efforts is the key to improving patient outcomes. Here, we describe the unique roles education and advocacy play in the care of children with AKI, discuss the importance of customizing educational outreach efforts to individual groups and contexts, and highlight the opportunities created through innovations and partnerships to optimize lifelong health outcomes...
November 7, 2023: Pediatric Nephrology
#5
EDITORIAL
Rajashree Rana, Matthew D Breyer
No abstract text is available yet for this article.
June 1, 2023: Journal of the American Society of Nephrology: JASN
#6
JOURNAL ARTICLE
Michael Eisenstein
No abstract text is available yet for this article.
March 2023: Nature
#7
EDITORIAL
Monica Vasiliu
No abstract text is available yet for this article.
January 12, 2023: Nephron
#8
JOURNAL ARTICLE
Stuart L Goldstein, Ayse Akcan-Arikan, Rashid Alobaidi, David J Askenazi, Sean M Bagshaw, Matthew Barhight, Erin Barreto, Benan Bayrakci, Orville N R Bignall, Erica Bjornstad, Patrick D Brophy, Rahul Chanchlani, Jennifer R Charlton, Andrea L Conroy, Akash Deep, Prasad Devarajan, Kristin Dolan, Dana Y Fuhrman, Katja M Gist, Stephen M Gorga, Jason H Greenberg, Denise Hasson, Emma Heydari Ulrich, Arpana Iyengar, Jennifer G Jetton, Catherine Krawczeski, Leslie Meigs, Shina Menon, Jolyn Morgan, Catherine J Morgan, Theresa Mottes, Tara M Neumayr, Zaccaria Ricci, David Selewski, Danielle E Soranno, Michelle Starr, Natalja L Stanski, Scott M Sutherland, Jordan Symons, Marcelo S Tavares, Molly Wong Vega, Michael Zappitelli, Claudio Ronco, Ravindra L Mehta, John Kellum, Marlies Ostermann, Rajit K Basu
IMPORTANCE: Increasing evidence indicates that acute kidney injury (AKI) occurs frequently in children and young adults and is associated with poor short-term and long-term outcomes. Guidance is required to focus efforts related to expansion of pediatric AKI knowledge. OBJECTIVE: To develop expert-driven pediatric specific recommendations on needed AKI research, education, practice, and advocacy. EVIDENCE REVIEW: At the 26th Acute Disease Quality Initiative meeting conducted in November 2021 by 47 multiprofessional international experts in general pediatrics, nephrology, and critical care, the panel focused on 6 areas: (1) epidemiology; (2) diagnostics; (3) fluid overload; (4) kidney support therapies; (5) biology, pharmacology, and nutrition; and (6) education and advocacy...
September 1, 2022: JAMA Network Open
#9
COMMENT
Letizia De Chiara, Yun Xia
No abstract text is available yet for this article.
September 2022: Kidney International
#10
EDITORIAL
Danielle E Soranno, Akash Deep, Katja M Gist, Michael Zappitelli
No abstract text is available yet for this article.
2021: Frontiers in Pediatrics
#11
JOURNAL ARTICLE
Hannah A I Schaubroeck, Diana Vargas, Wim Vandenberghe, Eric A J Hoste
BACKGROUND: A bundle of preventive measures can be taken to avoid acute kidney injury (AKI) or progression of AKI. We performed a systematic review and meta-analysis to evaluate the compliance to AKI care bundles in hospitalized patients and its impact on kidney and patient outcomes. METHODS: Randomized controlled trials, observational and interventional studies were included. Studied outcomes were care bundle compliance, occurrence of AKI and moderate-severe AKI, use of kidney replacement therapy (KRT), kidney recovery, mortality (ICU, in-hospital and 30-day) and length-of-stay (ICU, hospital)...
October 8, 2021: BMC Nephrology
#12
REVIEW
Marlies Ostermann, VinCent Wu, Dmitry Sokolov, Nuttha Lumlertgul
PURPOSE OF REVIEW: The current definition and classification of acute kidney injury (AKI) has limitations and shortcomings, which impact clinical management. The aim of this review is to highlight recent advances in our understanding of the pathophysiology and epidemiology of AKI, which impacts management and offers opportunities. RECENT FINDINGS: Kidney damage varies according to the type of primary insult, secondary effects and mitigating responses and leads to distinct molecular, cellular and functional changes...
December 1, 2021: Current Opinion in Critical Care
#13
REVIEW
Kai M Schmidt-Ott
One in five hospitalized patients suffers acute kidney injury (AKI). Depending on its severity, AKI is associated with an up to 15-fold increased risk of mortality and constitutes a major risk factor for subsequent cardiovascular events and for the development of chronic kidney disease. This concise review summarizes recently published studies, focusing on 1.) automated AKI detection using electronic health records-based AKI alert systems, 2.) renal replacement therapy and its optimal timing and anticoagulation regimen, and 3...
August 2021: Deutsche Medizinische Wochenschrift
#14
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
July 15, 2021: Nature Reviews. Disease Primers
#15
REVIEW
John A Kellum, Paola Romagnani, Gloria Ashuntantang, Claudio Ronco, Alexander Zarbock, Hans-Joachim Anders
Acute kidney injury (AKI) is defined by a sudden loss of excretory kidney function. AKI is part of a range of conditions summarized as acute kidney diseases and disorders (AKD), in which slow deterioration of kidney function or persistent kidney dysfunction is associated with an irreversible loss of kidney cells and nephrons, which can lead to chronic kidney disease (CKD). New biomarkers to identify injury before function loss await clinical implementation. AKI and AKD are a global concern. In low-income and middle-income countries, infections and hypovolaemic shock are the predominant causes of AKI...
July 15, 2021: Nature Reviews. Disease Primers
#16
REVIEW
Blaithin A McMahon, Lakhmir S Chawla
Loop diuretics are among the most widely used drugs worldwide and are commonly employed in the management of complications associated with acute kidney injury (AKI), namely volume overload and electrolyte management. The use of loop diuretics in critically ill patients with AKI is paramount to preventing or treating pulmonary edema. The naturetic response to a loop diuretic is based on its unique renal pharmacology. Our review article summarizes the pharmacology of furosemide in the intact nephron and discusses how this response might be altered by the presence of AKI...
December 2021: Renal Failure
#17
JOURNAL ARTICLE
Jianni Huang, George Bayliss, Shougang Zhuang
Pigs represent a potentially attractive model for medical research. Similar body size and physiological patterns of kidney injury that more closely mimic those described in humans make larger animals attractive for experimentation. Using larger animals, including pigs, to investigate the pathogenesis of acute kidney injury (AKI) also serves as an experimental bridge, narrowing the gap between clinical disease and preclinical discoveries. This article compares the advantages and disadvantages of large versus small AKI animal models and provides a comprehensive overview of the development and application of porcine models of AKI induced by clinically relevant insults, including ischemia-reperfusion, sepsis, and nephrotoxin exposure...
June 1, 2021: American Journal of Physiology. Renal Physiology
#18
JOURNAL ARTICLE
Raymond Vanholder, Eric Rondeau, Hans-Joachim Anders, Nicholas Carlson, Danilo Fliser, Mehmet Kanbay, José António Lopes, Patrick T Murray, Alberto Ortiz, Ana B Sanz, Nicholas M Selby, Andrzej Wiecek, Ziad A Massy
Acute Kidney Injury (AKI) is an often neglected but crucial element of clinical nephrology. The aim of the Nephrology Public Policy Committee (NPPC) of the European Renal Association - European Dialysis and Transplant Association (ERA-EDTA) is to promote several key aspects of European nephrology. One of the targets proposed by NPPC was to advance European nephrology involvement in AKI. We undertook literature analyses to define the current position of European nephrology in the field of AKI compared to other regions, and about how different European countries compare to each other...
February 2, 2021: Nephrology, Dialysis, Transplantation
#19
JOURNAL ARTICLE
Keitaro Nagata, Taro Horino, Yutaka Hatakeyama, Tatsuki Matsumoto, Yoshio Terada, Yoshiyasu Okuhara
AIM: To clarify the effects of the duration of acute damage and/or loss of renal function following an acute kidney injury event on the renal prognosis after recovery. METHODS: We retrospectively reviewed data collected between 1995 and 2016 from the Kochi Medical School Hospital. Patients were stratified according to the time required for recovery with fluid therapy (expected to reflect the presence of renal dysfunction): ≤2 days after onset, transient injury group (n = 491); 3 to 7 days after onset, persistent injury group (n = 1076); and ≥ 8 days after onset, acute kidney disease group (n = 1046)...
April 2021: Nephrology
#20
REVIEW
Jackcy Jacob, Joanne Dannenhoffer, Annie Rutter
Acute kidney injury (AKI) is defined as an increase in serum creatinine or a decrease in urine output over hours to days. A thorough history and physical examination can help categorize the underlying cause as prerenal, intrinsic renal, or postrenal. Initial evaluation and management of AKI in the community setting includes laboratory work-up, medication adjustment, identification and reversal of underlying cause, and referral to appropriate specialty care. Even one episode of AKI increases the risk of cardiovascular disease, chronic kidney disease, and death...
December 2020: Primary Care
Make the most of Read.
Download the mobile app.
Download the mobile app.
Fetching more papers... 
