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Crohn's

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By Brooke Manor Endocrinology
https://www.readbyqxmd.com/read/16115360/high-dose-fish-oil-and-antioxidants-in-crohn-s-disease-and-the-response-of-bone-turnover-a-randomised-controlled-trial
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RANDOMIZED CONTROLLED TRIAL
Timothy M Trebble, Mike A Stroud, Stephen A Wootton, Philip C Calder, David R Fine, Mark A Mullee, Caje Moniz, Nigel K Arden
Crohn's disease is associated with altered bone turnover that may be influenced by nutritional status, the systemic inflammatory response, cytokine production by circulating (peripheral blood) mononuclear cells (PBMC) and antioxidant micronutrient intake. High-dose fish oil is associated with reductions in disease relapse and inflammatory markers, and modulates PBMC function. The effect of fish oil plus antioxidants on bone turnover and PBMC function (the production of interferon-gamma and prostaglandin E2) in Crohn's disease was investigated in a randomised-controlled trial...
August 2005: British Journal of Nutrition
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