William A Bauman, Ann M Spungen, Joseph F Collins, Dennis W Raisch, Chester Ho, George A Deitrick, Bernard A Nemchausky, Lance L Goetz, Jai S Park, Michael Schwartz, John L Merritt, Vidya Jayawardena, Paul Sandford, Sunil Sabharwal, Sally A Holmes, Fahima Nasar, Roy Sasaki, Vandana Punj, Karin F Zachow, Walter C Chua, MaryKutty D Thomas, Rose C Trincher
BACKGROUND: Anabolic steroids have been reported to improve wound healing. OBJECTIVE: To determine whether oxandrolone increases the percentage of target pressure ulcers (TPUs) that heal compared with placebo and whether healed ulcers remain closed 8 weeks after treatment. DESIGN: Parallel-group, placebo-controlled, randomized trial conducted from 1 August 2005 to 30 November 2008. Patients, clinical care providers, study personnel, and statisticians were blinded to treatment assignment...
May 21, 2013: Annals of Internal Medicine