Annette McWilliams, Martin C Tammemagi, John R Mayo, Heidi Roberts, Geoffrey Liu, Kam Soghrati, Kazuhiro Yasufuku, Simon Martel, Francis Laberge, Michel Gingras, Sukhinder Atkar-Khattra, Christine D Berg, Ken Evans, Richard Finley, John Yee, John English, Paola Nasute, John Goffin, Serge Puksa, Lori Stewart, Scott Tsai, Michael R Johnston, Daria Manos, Garth Nicholas, Glenwood D Goss, Jean M Seely, Kayvan Amjadi, Alain Tremblay, Paul Burrowes, Paul MacEachern, Rick Bhatia, Ming-Sound Tsao, Stephen Lam
BACKGROUND: Major issues in the implementation of screening for lung cancer by means of low-dose computed tomography (CT) are the definition of a positive result and the management of lung nodules detected on the scans. We conducted a population-based prospective study to determine factors predicting the probability that lung nodules detected on the first screening low-dose CT scans are malignant or will be found to be malignant on follow-up. METHODS: We analyzed data from two cohorts of participants undergoing low-dose CT screening...
September 5, 2013: New England Journal of Medicine