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Antibiotics in General Surgery

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39 papers 100 to 500 followers
By Giovanni Gambino M.D. Ph.D.
Alice Charlotte Adelaide Murray, Ravi P Kiran
No abstract text is available yet for this article.
September 2016: Advances in Surgery
Marco Testa, Michela Stillo, Sebastian Giacomelli, Silvia Scoffone, Pier Angelo Argentero, Enzo Carlo Farina, Carla Maria Zotti
BACKGROUND: Surveillance of Surgical Site Infections (SSI) in 2010 found 39 % compliance with hospital guidelines in Piedmont (Italy). The aim of the study was to estimate the appropriate use of antimicrobial prophylaxis and compliance with hospitals guidelines in surgical wards. METHODS: This survey study took place in 21 surgery wards of 4 public hospitals. Forms were completed by public health resident doctors together with a medical ward referent and infection control nurses...
2015: BMC Surgery
Mostafa Mehrabi Bahar, Azadeh Jabbari Nooghabi, Mehdi Jabbari Nooghabi, Ali Jangjoo
OBJECTIVE: There are controversies about the benefits of prophylactic antibiotics in the prevention of postoperative surgical site infection (SSI) in mesh herniorrhaphy for a long time. This study aimed to evaluate the effectiveness and efficacy of systemic prophylactic cefazolin in prevention of wound infection in various types of hernia repair with mesh materials. METHODS: This is a prospective randomized control study. We evaluated wound infection rates in 395 patients with various kinds of hernia who underwent elective mesh repair using polypropylene mesh from 2007 to 2011...
July 2015: Asian Journal of Surgery
Shamik Dholakia, John Paul Jeans, Usman Khalid, Shruti Dholakia, Charlotte D'Souza, Kristof Nemeth
INTRODUCTION: Surgical-site infections (SSIs) are associated with an increased duration of hospital stay, poorer quality of life, and an marked increase in cost to the hospital. Lapses in compliance with aseptic principles are a substantial risk factor for SSI, which may be attributable to distractions such as noise during the operation. The aims of this study were to assess whether noise levels in the operating room are associated with the development of SSI and to elucidate the extent to which these levels affect the financial burden of surgery...
June 2015: Surgery
Yoshiki Okita, Minako Kobayashi, Toshimitsu Araki, Hiroyuki Fujikawa, Yuhki Koike, Koike Yuki, Kohei Otake, Otake Kohei, Inoue Mikihiro, Inoue Mikihiro, Yuji Toiyama, Toiyama Yuji, Masaki Ohi, Msaki Ohi, Koji Tanaka, Yasuhiro Inoue, Keiichi Uchida, Yasuhiko Mohri, Koichiro Yamakado, Masato Kusunoki
PURPOSE: The aims of this study were to reveal how using the antibiotics recommended by the 2010 Surgical Infection Society (SIS) and Infectious Disease Society of America (IDSA) guidelines can affect the therapeutic outcomes. METHODS: We reviewed the cases of 53 patients with a postoperative intra-abdominal abscess without anastomotic leakage after gastrointestinal surgery who underwent image-guided percutaneous abscess drainage (PAD) and concomitant antibiotic therapy...
August 2015: Surgery Today
Anirudh Srinivas, Lileswar Kaman, Prithivi Raj, Vikas Gautam, Divya Dahiya, Gurpreet Singh, Rajinder Singh, Bikash Medhi
PURPOSE: To compare the efficacy of chlorhexidine-gluconate versus povidone iodine in preoperative skin preparation in the prevention of surgical site infections (SSIs) in clean-contaminated upper abdominal surgeries. METHODS: This was a prospective randomized controlled trial conducted on patients undergoing clean-contaminated upper abdominal surgeries. A total of 351 patients 18-70 years old were randomized into two groups; chlorhexidine and povidone iodine skin preparation before surgery...
November 2015: Surgery Today
Faraaz de Belder
No abstract text is available yet for this article.
March 2016: Annals of Surgery
Melanie S Morris, Laura A Graham, Daniel I Chu, Jamie A Cannon, Mary T Hawn
OBJECTIVE: To determine the relationship between oral antibiotic bowel preparation (OABP) and surgical site infection (SSI) rates in a national colectomy cohort. BACKGROUND: OABP for elective colorectal surgery has fallen out of favor. Large cohort studies show that OABP is associated with a 50% reduction in SSI after colectomy. METHODS: A retrospective analysis of the National Surgical Quality Improvement Program colectomy cohort from 2011 to 2012 was performed to examine the association between use of OABP and outcomes of SSI, length of stay (LOS), and readmission after elective colectomy...
June 2015: Annals of Surgery
Andrea Romano, Punam Parikh, Patricia Byers, Nicholas Namias
BACKGROUND: According to the 2002 Surgical Infection Society Guidelines on Antimicrobial Therapy for Intra-abdominal Infections, antimicrobial therapy is not recommended beyond 24 hours for the treatment of postoperative acute or gangrenous appendicitis without perforation. However, clinicians commonly consider gangrenous appendicitis to pose a greater risk of post-operative infectious complications, such as surgical site infections and intra-abdominal abscesses. This study examines the relative risk of post-operative infection between patients with simple and gangrenous appendicitis...
October 2014: Surgical Infections
Jeffrey E Keenan, Paul J Speicher, Julie K M Thacker, Monica Walter, Maragatha Kuchibhatla, Christopher R Mantyh
IMPORTANCE: Surgical site infections (SSIs) in colorectal surgery are associated with increased morbidity and health care costs. OBJECTIVE: To determine the effect of a preventive SSI bundle (hereafter bundle) on SSI rates and costs in colorectal surgery. DESIGN: Retrospective study of institutional clinical and cost data. The study period was January 1, 2008, to December 31, 2012, and outcomes were assessed and compared before and after implementation of the bundle on July 1, 2011...
October 2014: JAMA Surgery
Samar M J Musmar, Hiba Ba'ba, Ala' Owais
BACKGROUND: Surgical site infection is a major contributor to increased mortality and health care costs globally which can be reduced by appropriate antibiotic prophylactic use. In Palestine, there is no published data about preoperative antibiotic use. This study aims to find the pattern of antimicrobial prophylaxis use by evaluating time of the first dose, antibiotic selection and duration after surgery in three governmental hospitals in North West Bank/ Palestine during 2011. METHODS: After approval of Institutional Review Board, a prospective cohort study included a total of 400 abdominal, orthopedic, and gynecological operations which were performed during study period...
2014: BMC Surgery
Talar Tejirian, L Andrew DiFronzo, Philip I Haigh
No abstract text is available yet for this article.
November 2006: Journal of the American College of Surgeons
G Tzovaras, S Delikoukos, G Christodoulides, M Spyridakis, F Mantzos, K Tepetes, E Athanassiou, C Hatzitheofilou
Hernia repair is one of the so-called clean operations. Many surgeons, however, use antibiotics, especially in the mesh repair era, without strong evidence to support this policy. We conducted a single-centre prospective randomised trial with a view to clarify this issue on a scientific basis. From January 2000 all patients undergoing elective inguinal hernia repair using a tension-free polypropylene mesh technique, provided they fulfilled predetermined criteria, were randomised to have a single dose of amoxicillin and clavoulanic acid or placebo in a double-blind manner...
February 2007: International Journal of Clinical Practice
John P Burke, P Ronan O'Connell
No abstract text is available yet for this article.
August 2014: Diseases of the Colon and Rectum
T J Aufenacker, M J W Koelemay, D J Gouma, M P Simons
BACKGROUND: The aim was to determine whether systemic antibiotic prophylaxis prevented wound infection after repair of abdominal wall hernia with mesh. METHODS: This was a systematic review of the available literature identified from multiple databases using the terms 'hernia' and 'antibiotic prophylaxis'. Randomized placebo-controlled trials of antibiotic prophylaxis in abdominal wall mesh hernia repair with explicitly defined wound infection criteria and a minimum follow-up of 1 month were included...
January 2006: British Journal of Surgery
J Reibetanz, C-T Germer
No abstract text is available yet for this article.
August 2014: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
Mohammad Ali Hesami, Hamid Alipour, Hamed Nikoupour Daylami, Bijan Alipour, Shahrzad Bazargan-Hejazi, Alireza Ahmadi
BACKGROUND: Perforated appendicitis is one of the most common causes of acute abdomen requiring emergent surgery for immediate appendectomy and peritoneal cavity irrigation; however, the efficacy of irrigation with antibiotic solutions is controversial. OBJECTIVES: The aim of this study was to assess the efficacy of imipenem solution irrigation on post-operative surgical site infections (SSIs), hospital length of stay, and hospital costs. We hypothesized that there would be lower rate of SSIs, a shorter hospital stay, and lower hospital cost in patients with perforated appendicitis who received peritoneal cavity irrigation with imipenem solution in comparison to their counterparts who received irrigation with normal saline...
April 2014: Iranian Red Crescent Medical Journal
Zhi-Hua Liu, Chao Li, Xing-Wei Zhang, Liang Kang, Jian-Ping Wang
Appendicectomy has been the gold standard treatment of acute appendicitis for more than a century, while nonoperative therapies, including antibiotics, have acquired increased interest in recent years. The present meta-analysis aimed to compare the therapeutic effects of antibiotics versus appendicectomy for the treatment of acute appendicitis. Medline, Embase and The Cochrane Library databases were searched. Prospective randomized controlled trials that compared antibiotic treatment with surgery were included...
May 2014: Experimental and Therapeutic Medicine
Hyoung-Chul Park, Min Jeong Kim, Bong Hwa Lee
PURPOSE: Although many patients receive antibiotic therapy for appendicitis, it is unclear if this treatment can be administered to elderly patients. We aimed to assess the outcomes of antibiotic therapy for appendicitis in elderly patients aged ≥80 years. METHOD: During this 4-year study, we enrolled 26 elderly patients who initially received antibiotic therapy. Of these, 3 were suspected to have complicated appendicitis. Antibiotic therapy consisted of second-generation cephalosporin and metronidazole that was administered for 4 days with a 24-hour fasting period...
June 2014: American Journal of Medicine
Hyoung-Chul Park, Min Jeong Kim, Bong Hwa Lee
PURPOSE: Although many patients receive antibiotic therapy for uncomplicated appendicitis, the relatively high treatment failure and recurrence rates are problematic. We assumed that patients with appendicitis and appendiceal diameters ≤ 10 mm, have better outcomes. The purpose of this prospective non-randomized study was to assess the outcomes of antibiotic therapy in patients with uncomplicated appendicitis and appendiceal diameters ≤ 10 mm. METHODS: Over 2 years, we enrolled 119 patients who initially received antibiotic therapy...
2014: International Journal of Surgery
2014-07-23 17:02:52
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