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Essential Urology

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137 papers 100 to 500 followers
By Axel Cayetano Urology Resident
https://www.readbyqxmd.com/read/26719015/testosterone-therapy-in-men-with-prostate-cancer
#1
REVIEW
Alan L Kaplan, Jim C Hu, Abraham Morgentaler, John P Mulhall, Claude C Schulman, Francesco Montorsi
CONTEXT: The use of testosterone therapy in men with prostate cancer was previously contraindicated, although recent data challenge this axiom. Over the past 2 decades, there has been a dramatic paradigm shift in beliefs, attitude, and treatment of testosterone deficiency in men with prostate cancer. OBJECTIVE: To summarize and analyze current literature regarding the effect of testosterone replacement in men with prostate cancer. EVIDENCE ACQUISITION: We conducted a Medline search to identify all publications related to testosterone therapy in both treated and untreated prostate cancer...
May 2016: European Urology
https://www.readbyqxmd.com/read/27614693/partial-nephrectomy-versus-radical-nephrectomy-for-clinical-t1b-and-t2-renal-tumors-a-systematic-review-and-meta-analysis-of-comparative-studies
#2
REVIEW
Maria Carmen Mir, Ithaar Derweesh, Francesco Porpiglia, Homayoun Zargar, Alexandre Mottrie, Riccardo Autorino
BACKGROUND: Partial nephrectomy (PN) is the reference standard of management for a cT1a renal mass. However, its role in the management of larger tumors (cT1b and cT2) is still under scrutiny. OBJECTIVE: To conduct a meta-analysis assessing functional, oncologic, and perioperative outcomes of PN and radical nephrectomy (RN) in the specific case of larger renal tumors (≥cT1b). The primary endpoint was an overall analysis of cT1b and cT2 masses. The secondary endpoint was a sensitivity analysis for cT2 only...
September 7, 2016: European Urology
https://www.readbyqxmd.com/read/27591931/eau-estro-siog-guidelines-on-prostate-cancer-part-ii-treatment-of-relapsing-metastatic-and-castration-resistant-prostate-cancer
#3
Philip Cornford, Joaquim Bellmunt, Michel Bolla, Erik Briers, Maria De Santis, Tobias Gross, Ann M Henry, Steven Joniau, Thomas B Lam, Malcolm D Mason, Henk G van der Poel, Theo H van der Kwast, Olivier Rouvière, Thomas Wiegel, Nicolas Mottet
OBJECTIVE: To present a summary of the 2016 version of the European Association of Urology (EAU) - European Society for Radiotherapy & Oncology (ESTRO) - International Society of Geriatric Oncology (SIOG) Guidelines on the treatment of relapsing, metastatic, and castration-resistant prostate cancer (CRPC). EVIDENCE ACQUISITION: The working panel performed a literature review of the new data (2013-2015). The guidelines were updated, and the levels of evidence and/or grades of recommendation were added based on a systematic review of the literature...
August 31, 2016: European Urology
https://www.readbyqxmd.com/read/27626136/10-year-outcomes-after-monitoring-surgery-or-radiotherapy-for-localized-prostate-cancer
#4
Freddie C Hamdy, Jenny L Donovan, J Athene Lane, Malcolm Mason, Chris Metcalfe, Peter Holding, Michael Davis, Tim J Peters, Emma L Turner, Richard M Martin, Jon Oxley, Mary Robinson, John Staffurth, Eleanor Walsh, Prasad Bollina, James Catto, Andrew Doble, Alan Doherty, David Gillatt, Roger Kockelbergh, Howard Kynaston, Alan Paul, Philip Powell, Stephen Prescott, Derek J Rosario, Edward Rowe, David E Neal
Background The comparative effectiveness of treatments for prostate cancer that is detected by prostate-specific antigen (PSA) testing remains uncertain. Methods We compared active monitoring, radical prostatectomy, and external-beam radiotherapy for the treatment of clinically localized prostate cancer. Between 1999 and 2009, a total of 82,429 men 50 to 69 years of age received a PSA test; 2664 received a diagnosis of localized prostate cancer, and 1643 agreed to undergo randomization to active monitoring (545 men), surgery (553), or radiotherapy (545)...
October 13, 2016: New England Journal of Medicine
https://www.readbyqxmd.com/read/27238616/surgical-management-of-stones-american-urological-association-endourological-society-guideline-part-i
#5
Dean Assimos, Amy Krambeck, Nicole L Miller, Manoj Monga, M Hassan Murad, Caleb P Nelson, Kenneth T Pace, Vernon M Pais, Margaret S Pearle, Glenn M Preminger, Hassan Razvi, Ojas Shah, Brian R Matlaga
PURPOSE: This Guideline is intended to provide a clinical framework for the surgical management of patients with kidney and/or ureteral stones. The summary presented herein represents Part I of the two-part series dedicated to Surgical Management of Stones: American Urological Association/Endourological Society Guideline. Please refer to Part II for an in-depth discussion of patients presenting with ureteral or renal stones. MATERIALS AND METHODS: A systematic review of the literature (search dates 1/1/1985 to 5/31/2015) was conducted to identify peer-reviewed studies relevant to the surgical management of stones...
October 2016: Journal of Urology
https://www.readbyqxmd.com/read/27375033/updated-2016-eau-guidelines-on-muscle-invasive-and-metastatic-bladder-cancer
#6
J Alfred Witjes, Thierry Lebret, Eva M Compérat, Nigel C Cowan, Maria De Santis, Harman Maxim Bruins, Virginia Hernández, Estefania Linares Espinós, James Dunn, Mathieu Rouanne, Yann Neuzillet, Erik Veskimäe, Antoine G van der Heijden, Georgios Gakis, Maria J Ribal
CONTEXT: Invasive bladder cancer is a frequently occurring disease with a high mortality rate despite optimal treatment. The European Association of Urology (EAU) Muscle-invasive and Metastatic Bladder Cancer (MIBC) Guidelines are updated yearly and provides information to optimise diagnosis, treatment, and follow-up of this patient population. OBJECTIVE: To provide a summary of the EAU guidelines for physicians and patients confronted with muscle-invasive and metastatic bladder cancer...
June 30, 2016: European Urology
https://www.readbyqxmd.com/read/27394644/preoperative-membranous-urethral-length-measurement-and-continence-recovery-following-radical-prostatectomy-a-systematic-review-and-meta-analysis
#7
Sean F Mungovan, Jaspreet S Sandhu, Oguz Akin, Neil A Smart, Petra L Graham, Manish I Patel
CONTEXT: Membranous urethral length (MUL) measured prior to radical prostatectomy (RP) has been identified as a factor that is associated with the recovery of continence following surgery. OBJECTIVE: To undertake a systematic review and meta-analysis of all studies reporting the effect of MUL on the recovery of continence following RP. EVIDENCE ACQUISITION: A comprehensive search of PubMed, EMBASE, and Scopus databases up to September 2015 was performed...
July 6, 2016: European Urology
https://www.readbyqxmd.com/read/27324428/eau-guidelines-on-non-muscle-invasive-urothelial-carcinoma-of-the-bladder-update-2016
#8
Marko Babjuk, Andreas Böhle, Maximilian Burger, Otakar Capoun, Daniel Cohen, Eva M Compérat, Virginia Hernández, Eero Kaasinen, Joan Palou, Morgan Rouprêt, Bas W G van Rhijn, Shahrokh F Shariat, Viktor Soukup, Richard J Sylvester, Richard Zigeuner
CONTEXT: The European Association of Urology (EAU) panel on Non-muscle-invasive Bladder Cancer (NMIBC) released an updated version of the guidelines on Non-muscle-invasive Bladder Cancer. OBJECTIVE: To present the 2016 EAU guidelines on NMIBC. EVIDENCE ACQUISITION: A broad and comprehensive scoping exercise covering all areas of the NMIBC guidelines published between April 1, 2014, and May 31, 2015, was performed. Databases covered by the search included Medline, Embase, and the Cochrane Libraries...
June 17, 2016: European Urology
https://www.readbyqxmd.com/read/27215686/evidence-based-management-guidelines-on-peyronie-s-disease
#9
Eric Chung, David Ralph, Ates Kagioglu, Guilio Garaffa, Ahmed Shamsodini, Trinity Bivalacqua, Sidney Glina, Lawrence Hakim, Hossein Sadeghi-Nejad, Gregory Broderick
INTRODUCTION: Despite recent advances in our knowledge and treatment strategies in Peyronie's Disease (PD), much remained unknown about this disease. AIM: To provide a clinical framework and key guideline statements to assist clinicians in an evidence-based management of PD. METHODS: A systematic literature search was conducted to identify published literature relevant to PD. The search included all relevant articles published up to June 2015, including preclinical studies and published guidelines...
June 2016: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/27176559/neurogenic-lower-urinary-tract-dysfunction-clinical-management-recommendations-of-the-neurologic-incontinence-committee-of-the-fifth-international-consultation-on-incontinence-2013
#10
REVIEW
Marcus John Drake, Apostolos Apostolidis, Andrea Cocci, Anton Emmanuel, Jerzy B Gajewski, Simon C W Harrison, John P F A Heesakkers, Gary E Lemack, Helmut Madersbacher, Jalesh N Panicker, Piotr Radziszewski, Ryuji Sakakibara, Jean Jacques Wyndaele
BACKGROUND: Evidence-based guidelines for the management of neurological disease and lower urinary tract dysfunction have been produced by the International Consultations on Incontinence (ICI). These are comprehensive guidelines, and were developed to have world-wide relevance. AIMS: To update clinical management of neurogenic bladder dysfunction from the recommendations of the fourth ICI, 2009. MATERIALS AND METHODS: A series of evidence reviews and updates were performed by members of the working group...
August 2016: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/27164287/the-future-of-enhanced-recovery-for-radical-cystectomy-current-evidence-barriers-to-adoption-and-the-next-steps
#11
Bernard J Danna, Erika L Wood, Janet E Baack Kukreja, Jay B Shah
Radical cystectomy (RC) is a complex procedure that can involve long postoperative hospital stays and complicated, burdensome recoveries. Enhanced recovery after surgery is a broad term encompassing an overall approach to perioperative management of postsurgical patients and is becoming more widely accepted for cystectomy patients. This review examines the current evidence for using enhanced recovery protocols for RC as well as current rates of adoption of enhanced recovery among urologists performing RC. We also discuss the next steps for overcoming barriers to the widespread implementation of enhanced recovery for RC...
October 2016: Urology
https://www.readbyqxmd.com/read/25626035/comparison-of-mr-ultrasound-fusion-guided-biopsy-with-ultrasound-guided-biopsy-for-the-diagnosis-of-prostate-cancer
#12
COMPARATIVE STUDY
M Minhaj Siddiqui, Soroush Rais-Bahrami, Baris Turkbey, Arvin K George, Jason Rothwax, Nabeel Shakir, Chinonyerem Okoro, Dima Raskolnikov, Howard L Parnes, W Marston Linehan, Maria J Merino, Richard M Simon, Peter L Choyke, Bradford J Wood, Peter A Pinto
IMPORTANCE: Targeted magnetic resonance (MR)/ultrasound fusion prostate biopsy has been shown to detect prostate cancer. The implications of targeted biopsy alone vs standard extended-sextant biopsy or the 2 modalities combined are not well understood. OBJECTIVE: To assess targeted vs standard biopsy and the 2 approaches combined for the diagnosis of intermediate- to high-risk prostate cancer. DESIGN, SETTING, AND PARTICIPANTS: Prospective cohort study of 1003 men undergoing both targeted and standard biopsy concurrently from 2007 through 2014 at the National Cancer Institute in the United States...
January 27, 2015: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/19689582/surgery-illustrated-surgical-atlas-robotic-radical-cystectomy-in-the-male
#13
Nicolo Buffi, Alexandre Mottrie, Giovanni Lughezzani, Nikos Koliakos, Peter Schatteman, Paul Carpentier, Etyenne Fonteyne
No abstract text is available yet for this article.
September 2009: BJU International
https://www.readbyqxmd.com/read/24182975/vasectomy
#14
REVIEW
Matthew D Rogers, Peter N Kolettis
This article is intended to familiarize the surgeon with all aspects of vasectomy including preoperative counseling, anesthetic techniques, surgical techniques, postoperative follow-up, and postvasectomy semen analysis. The latest literature regarding the complication rates and failure rates of various vas occlusion techniques is also discussed.
November 2013: Urologic Clinics of North America
https://www.readbyqxmd.com/read/27153766/role-of-prostate-artery-embolization-in-the-management-of-refractory-haematuria-of-prostatic-origin
#15
REVIEW
Keith Pereira, Joshua A Halpern, Timothy D McClure, Nicholas A Lewis, Isaam Kably, Shivank Bhatia, Jim C Hu
Prostatic haematuria is among the most common genitourinary complaints of emergency room visits, distressing and troublesome to men and a challenging clinical problem to the treating physician. The most common aetiologies of prostatic haematuria include benign prostatic hyperplasia and prostate cancer. Prostatic haematuria usually resolves with conservative and medical methods; failure of these interventions results in refractory haematuria of prostatic origin (RHPO), a potentially life-threatening scenario...
September 2016: BJU International
https://www.readbyqxmd.com/read/27160478/can-short-term-hormone-therapy-for-rising-psa-prolong-survival
#16
Anthony V D'Amico
No abstract text is available yet for this article.
June 2016: Lancet Oncology
https://www.readbyqxmd.com/read/27144870/reevaluating-psa-testing-rates-in-the-plco-trial
#17
LETTER
Jonathan E Shoag, Sameer Mittal, Jim C Hu
No abstract text is available yet for this article.
May 5, 2016: New England Journal of Medicine
https://www.readbyqxmd.com/read/27132575/testosterone-therapies
#18
REVIEW
Mohit Khera
There are numerous testosterone formulations now available, and patients and clinicians should take into account the "4 Cs": cost, compliance, convenience, and concentration levels. Testosterone is a natural contraceptive and should not be used in men trying to achieve a pregnancy. All testosterone gels and solutions have an increased risk of transference, and there should be increased caution when in contact with children and pregnant women.
May 2016: Urologic Clinics of North America
https://www.readbyqxmd.com/read/27132576/testosterone-and-male-infertility
#19
REVIEW
Samuel J Ohlander, Mark C Lindgren, Larry I Lipshultz
Hypogonadism and its therapies have a significant impact on male fertility potential. It is necessary to determine the etiology to treat and counsel the patient appropriately on therapeutic options. For the hypogonadal male on exogenous testosterone, management should begin with cessation of the exogenous testosterone and supplemental subcutaneous human chorionic gonadotropin and an oral follicle-stimulating hormone (FSH)-inducing agent to allow reestablishment of the hypothalamic-pituitary-gonadal axis and spermatogenesis...
May 2016: Urologic Clinics of North America
https://www.readbyqxmd.com/read/27083114/magnetic-resonance-ultrasound-fusion-prostate-biopsy-in-the-diagnosis-of-prostate-cancer
#20
REVIEW
Mark D Tyson, Sandeep S Arora, Kristen R Scarpato, Daniel Barocas
The advent of multiparametric magnetic resonance imaging (MRI) has ushered in a new era for urologists who perform prostate needle biopsies. The fusion of MRI with transrectal ultrasound (US) allows the direct targeting of suspicious lesions, which has been shown to improve the performance of conventional random biopsy techniques by increasing detection of clinically relevant disease while also decreasing detection of low-risk cancer. However, as with any new technology, many questions regarding effectiveness, reproducibility, and generalizability still remain...
July 2016: Urologic Oncology
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