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By Brian Still Physician
Marius K Nickel, Cerstin Nickel, Moritz Muehlbacher, Peter K Leiberich, Patrick Kaplan, Claas Lahmann, Karin Tritt, Jakub Krawczyk, Christian Kettler, Christoph Egger, Wolfhardt K Rother, Thomas H Loew
The aim of this study was to compare the efficacy of topiramate versus a placebo in the treatment of adiposity in women undergoing olanzapine therapy. We also assessed changes health-related quality of life, the patient's actual state of health, and psychologic impairments. The 10-week, random, double-blind, placebo-controlled study included 43 women who had been treated with olanzapine (mean dose 7.8 +/- 3.6 in the topiramate group and 7.2 +/- 3.1 in the placebo group) and had gained weight as a side effect...
June 2005: Journal of Clinical Psychopharmacology
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