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Meta analisis compara las distintas estatinas en cuanto a seguridad

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Huseyin Naci, Jasper Brugts, Tony Ades
BACKGROUND: Our objective was to estimate the comparative harms of individual statins using both placebo-controlled and active-comparator trials. METHODS AND RESULTS: We systematically reviewed randomized trials evaluating different statins in participants with and without cardiovascular disease. We performed random-effects pairwise and network meta-analyses to quantify the relative harms of individual statins. We included 55 two-armed placebo-controlled and 80 two- or multiarmed active-comparator trials including 246,955 individuals...
July 2013: Circulation. Cardiovascular Quality and Outcomes
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