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1 papers 0 to 25 followers Radiation Oncology
Joanne S Haviland, J Roger Owen, John A Dewar, Rajiv K Agrawal, Jane Barrett, Peter J Barrett-Lee, H Jane Dobbs, Penelope Hopwood, Pat A Lawton, Brian J Magee, Judith Mills, Sandra Simmons, Mark A Sydenham, Karen Venables, Judith M Bliss, John R Yarnold
BACKGROUND: 5-year results of the UK Standardisation of Breast Radiotherapy (START) trials suggested that lower total doses of radiotherapy delivered in fewer, larger doses (fractions) are at least as safe and effective as the historical standard regimen (50 Gy in 25 fractions) for women after primary surgery for early breast cancer. In this prespecified analysis, we report the 10-year follow-up of the START trials testing 13 fraction and 15 fraction regimens. METHODS: From 1999 to 2002, women with completely excised invasive breast cancer (pT1-3a, pN0-1, M0) were enrolled from 35 UK radiotherapy centres...
October 2013: Lancet Oncology
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