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Sefation vacation FAIL

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By Jason Mann No BS pulmonary critical care fellow
Sangeeta Mehta, Lisa Burry, Deborah Cook, Dean Fergusson, Marilyn Steinberg, John Granton, Margaret Herridge, Niall Ferguson, John Devlin, Maged Tanios, Peter Dodek, Robert Fowler, Karen Burns, Michael Jacka, Kendiss Olafson, Yoanna Skrobik, Paul H├ębert, Elham Sabri, Maureen Meade
CONTEXT: Protocolized sedation and daily sedation interruption are 2 strategies to minimize sedation and reduce the duration of mechanical ventilation and intensive care unit (ICU) stay. We hypothesized that combining these strategies would augment the benefits. OBJECTIVE: To compare protocolized sedation with protocolized sedation plus daily sedation interruption in critically ill patients. DESIGN, SETTING, AND PATIENTS: Randomized controlled trial of 430 critically ill, mechanically ventilated adults conducted in 16 tertiary care medical and surgical ICUs in Canada and the United States between January 2008 and July 2011...
November 21, 2012: JAMA: the Journal of the American Medical Association
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