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Sarcoidosis full review 2013 LANCET

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2 papers 500 to 1000 followers
By Jason Mann No BS pulmonary critical care fellow
https://www.readbyqxmd.com/read/21037016/a-concise-review-of-pulmonary-sarcoidosis
#1
REVIEW
Robert P Baughman, Daniel A Culver, Marc A Judson
This is an update on sarcoidosis, focusing on etiology, diagnosis, and treatment. In the area of etiopathogenesis, we now have a better understanding of the immune response that leads to the disease as well as genetic factors that modify both the risk for the disease and its clinical outcome. Several groups have also identified possible agents as a cause for sarcoidosis. Although none of these potential causes has been definitely confirmed, there is increasing evidence to support that one or more infectious agents may cause sarcoidosis, although this organism may no longer be viable in the patient...
March 1, 2011: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/24090799/sarcoidosis
#2
REVIEW
Dominique Valeyre, Antje Prasse, Hilario Nunes, Yurdagul Uzunhan, Pierre-Yves Brillet, Joachim Müller-Quernheim
Sarcoidosis is a systemic disease of unknown cause that is characterised by the formation of immune granulomas in various organs, mainly the lungs and the lymphatic system. Studies show that sarcoidosis might be the result of an exaggerated granulomatous reaction after exposure to unidentified antigens in individuals who are genetically susceptible. Several new insights have been made, particularly with regards to the diagnosis and care of some important manifestations of sarcoidosis. The indications for endobronchial ultrasound in diagnosis and for PET in the assessment of inflammatory activity are now better specified...
March 29, 2014: Lancet
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