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Critical Rsp

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2 papers 0 to 25 followers
By Ahgiel Jimenez Critical care medicine Dr and Emergency medicine Dr.
https://www.readbyqxmd.com/read/30247273/beyond-low-tidal-volume-ventilation-treatment-adjuncts-for-severe-respiratory-failure-in-acute-respiratory-distress-syndrome
#1
Vikram Fielding-Singh, Michael A Matthay, Carolyn S Calfee
OBJECTIVES: Despite decades of research, the acute respiratory distress syndrome remains associated with significant morbidity and mortality. This Concise Definitive Review provides a practical and evidence-based summary of treatments in addition to low tidal volume ventilation and their role in the management of severe respiratory failure in acute respiratory distress syndrome. DATA SOURCES: We searched the PubMed database for clinical trials, observational studies, and review articles describing treatment adjuncts in acute respiratory distress syndrome patients, including high positive end-expiratory pressure strategies, recruitment maneuvers, high-frequency oscillatory ventilation, neuromuscular blockade, prone positioning, inhaled pulmonary vasodilators, extracorporeal membrane oxygenation, glucocorticoids, and renal replacement therapy...
November 2018: Critical Care Medicine
https://www.readbyqxmd.com/read/29793554/acute-lung-injury-how-to-stabilize-a-broken-lung
#2
Gary F Nieman, Penny Andrews, Joshua Satalin, Kailyn Wilcox, Michaela Kollisch-Singule, Maria Madden, Hani Aiash, Sarah J Blair, Louis A Gatto, Nader M Habashi
The pathophysiology of acute respiratory distress syndrome (ARDS) results in heterogeneous lung collapse, edema-flooded airways and unstable alveoli. These pathologic alterations in alveolar mechanics (i.e. dynamic change in alveolar size and shape with each breath) predispose the lung to secondary ventilator-induced lung injury (VILI). It is our viewpoint that the acutely injured lung can be recruited and stabilized with a mechanical breath until it heals, much like casting a broken bone until it mends. If the lung can be "casted" with a mechanical breath, VILI could be prevented and ARDS incidence significantly reduced...
May 24, 2018: Critical Care: the Official Journal of the Critical Care Forum
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