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9 papers 0 to 25 followers Articulos de interes Neumología
Paul A Bergl
No abstract text is available yet for this article.
October 30, 2018: American Journal of Respiratory and Critical Care Medicine
Pamela J McShane, Gregory Tino
Bronchiectasis is an important clinical syndrome due to its increasing prevalence, significant economic burden on healthcare, and associated morbidity. Until recently, the disease was considered an "orphan" and essentially neglected from a therapeutic standpoint. Fortunately, many recent advances have been made in the field. Several national registries have formed to provide databases from which to study bronchiectasis patients. Experts published a consensus definition of a bronchiectasis-specific exacerbation which will serve as a unified definition for future clinical trials...
November 4, 2018: Chest
Jason D Chodakowski, D Mark Courtney
PURPOSE OF REVIEW: We provide a timely update on treatment care issues facing clinicians and patients with acute pulmonary embolism accompanied by either right ventricular strain (sub-massive pulmonary embolism) or shock (massive pulmonary embolism). RECENT FINDINGS: Care and research changes over the last several years have resulted in four important trends: more consensus and accuracy in the way acute pulmonary embolism severity is described and communicated among acute care clinicians and researchers, increased availability and use of risk prediction scoring systems, increased use of advanced invasive therapy in the setting of severe right ventricular dysfunction, and emergence of multidisciplinary pulmonary embolism response teams to guide standard care decision-making...
December 2018: Current Opinion in Critical Care
Fernando J Martinez, David J Lederer
As seen in this CME online activity (available at, idiopathic pulmonary fibrosis (IPF) is a specific form of chronic, progressive, fibrotic lung disease of unknown cause that is associated with substantial health-care utilization and high rates of mortality. The clinical symptoms of IPF are nonspecific and overlap with many pulmonary and cardiac diseases making differential diagnosis challenging. The American Thoracic Society/European Respiratory Society/Japanese Respiratory Society/Latin American Thoracic Association (ATS/ERS/JRS/ALAT) guidelines strongly recommend a multidisciplinary approach to the diagnosis of interstitial lung diseases; however, there are several limitations to the feasibility of this approach in clinical practice...
October 2018: Chest
Victor Kim, Shawn D Aaron
Chronic Obstructive Pulmonary Disease (COPD) is a chronic illness that may be periodically punctuated by exacerbations, characterised by acute worsening of dyspnea, and/or cough and sputum production, and/or increased sputum purulence. COPD exacerbations are common and carry with them important clinical and economic consequences including lost work productivity, increased utilisation of health care resources, temporary or permanent reductions in lung function and exercise capacity, hospitalisation, and sometimes death...
September 20, 2018: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
Scott C Bell, Joseph S Elborn, Catherine A Byrnes
Interest in bronchiectasis has increased over the past two decades, as shown by the establishment of disease-specific registries in several countries, the publication of management guidelines and a growing number of clinical trials to address evidence gaps for treatment decisions. This review considers the evidence for defining and treating pulmonary exacerbations, the approaches for eradication of newly identified airway pathogens and the methods to prevent exacerbations through long-term treatments from a pragmatic practice-based perspective...
November 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
Diego J Maselli, Megan Hardin, Stephanie A Christenson, Nicola A Hanania, Craig P Hersh, Sandra G Adams, Antonio Anzueto, Jay I Peters, MeiLan K Han, Fernando J Martinez
Over the last few years, there has been a renewed interest in patients with characteristics of both asthma and COPD. Although the precise definition of asthma-COPD overlap (ACO) is still controversial, patients with overlapping features are frequently encountered in clinical practice, and may indeed have worse clinical outcomes and increased health-care utilization than those with asthma or COPD. Therefore, there is a critical need to set a framework for the therapeutic approach of such patients. There are key distinctions in the therapy between asthma and COPD, particularly regarding the initial choice of therapy...
August 2, 2018: Chest
Zofia Zwolska, Ewa Augustynowicz-Kopeć
Drug-resistant tuberculosis, and particularly multidrug-resistant tuberculosis (MDR-TB) and extensive drug resistant TB (XDR-TB) as an increasing health problem and a serious challenge to TB control programs. MDR-Tb and XDR-TB are highly lethal in people living with HIV, with case of fatality rates of over 90%. At the same time, there are not many drugs effective in TB chemotherapy. Information about susceptibility patterns of Mycobacterium tuberculosis isolates against antituberculosis drugs is important aspect of tuberculosis control, and surveillance and analysis of local rates of TB drug resistance is helpful in the detection and monitoring of the extent of MDR and XDR strains, indicating the quality of TB control in the country...
May 2011: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
Christian Viniol, Claus F Vogelmeier
Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide. While COPD is a mainly chronic disease, a substantial number of patients suffer from exacerbations. Severe exacerbations are related to a significantly worse survival outcome. This review summarises the current knowledge on the different aspects of COPD exacerbations. The impact of risk factors and triggers such as smoking, severe airflow limitation, bronchiectasis, bacterial and viral infections and comorbidities is discussed...
March 31, 2018: European Respiratory Review: An Official Journal of the European Respiratory Society
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