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Ryan Ungaro, Saurabh Mehandru, Patrick B Allen, Laurent Peyrin-Biroulet, Jean-Frédéric Colombel
Ulcerative colitis is a chronic inflammatory disease affecting the colon, and its incidence is rising worldwide. The pathogenesis is multifactorial, involving genetic predisposition, epithelial barrier defects, dysregulated immune responses, and environmental factors. Patients with ulcerative colitis have mucosal inflammation starting in the rectum that can extend continuously to proximal segments of the colon. Ulcerative colitis usually presents with bloody diarrhoea and is diagnosed by colonoscopy and histological findings...
April 29, 2017: Lancet
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John M Findlay, Jihène El Kafsi, Clare Hammer, Jeffrey Gilmour, Richard S Gillies, Nicholas D Maynard
No abstract text is available yet for this article.
December 2016: Journal of the American College of Surgeons
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