Sarah Ringold, Sheila T Angeles-Han, Timothy Beukelman, Daniel Lovell, Carlos A Cuello, Mara L Becker, Robert A Colbert, Brian M Feldman, Polly J Ferguson, Harry Gewanter, Jaime Guzman, Jennifer Horonjeff, Peter A Nigrovic, Michael J Ombrello, Murray H Passo, Matthew L Stoll, C Egla Rabinovich, Rayfel Schneider, Olha Halyabar, Kimberly Hays, Amit Aakash Shah, Nancy Sullivan, Ann Marie Szymanski, Marat Turgunbaev, Amy Turner, James Reston
OBJECTIVE: To develop treatment recommendations for children with juvenile idiopathic arthritis manifesting as non-systemic polyarthritis, sacroiliitis, or enthesitis. METHODS: The Patient/Population, Intervention, Comparison, and Outcomes (PICO) questions were developed and refined by members of the guideline development teams. A systematic review was conducted to compile evidence for the benefits and harms associated with treatments for these conditions. GRADE (Grading of Recommendations Assessment, Development and Evaluation) methodology was used to rate the quality of evidence...
June 2019: Arthritis & Rheumatology