collection
MENU ▼
Read by QxMD icon Read
search

OBESITY 2017

shared collection
4 papers 0 to 25 followers
By EFRAIN PAEZ Internal Medicine since 1988. Interested in all aspects of Medicine.
https://www.readbyqxmd.com/read/29027993/current-pharmacotherapy-for-obesity
#1
REVIEW
Gitanjali Srivastava, Caroline M Apovian
More than one-third of adults in the USA have obesity, which causes, exacerbates or adversely impacts numerous medical comorbidities, including diabetes mellitus and cardiovascular disease. Despite intensive lifestyle modifications, the disease severity warrants further aggressive intervention, including pharmacotherapy, medical devices and bariatric surgery. Noninvasive anti-obesity drugs have thus now resurfaced as targeted adjunctive therapeutic approaches to intensive lifestyle intervention, bridging the gap between lifestyle and bariatric surgery...
January 2018: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/25843910/the-brown-fat-secretome-metabolic-functions-beyond-thermogenesis
#2
REVIEW
Guo-Xiao Wang, Xu-Yun Zhao, Jiandie D Lin
Brown fat is highly active in fuel oxidation and dissipates chemical energy through uncoupling protein (UCP)1-mediated heat production. Activation of brown fat leads to increased energy expenditure, reduced adiposity, and lower plasma glucose and lipid levels, thus contributing to better homeostasis. Uncoupled respiration and thermogenesis have been considered to be responsible for the metabolic benefits of brown adipose tissue. Recent studies have demonstrated that brown adipocytes also secrete factors that act locally and systemically to influence fuel and energy metabolism...
May 2015: Trends in Endocrinology and Metabolism: TEM
https://www.readbyqxmd.com/read/28759403/metformin-for-obesity-in-prepubertal-and-pubertal-children-a-randomized-controlled-trial
#3
RANDOMIZED CONTROLLED TRIAL
Belén Pastor-Villaescusa, M Dolores Cañete, Javier Caballero-Villarraso, Raúl Hoyos, Miriam Latorre, Rocío Vázquez-Cobela, Julio Plaza-Díaz, José Maldonado, Gloria Bueno, Rosaura Leis, Ángel Gil, Ramón Cañete, Concepción M Aguilera
OBJECTIVES: Metformin has shown its effectiveness in treating obesity in adults. However, little research has been conducted in children, with a lack of attention on pubertal status. The objectives were to determine whether oral metformin treatment reduces BMI z score, cardiovascular risk, and inflammation biomarkers in children who are obese depending on pubertal stage and sex. METHODS: This was a randomized, prospective, double-blind, placebo-controlled, multicenter trial, stratified according to pubertal stage and sex, conducted at 4 Spanish clinical hospitals...
July 2017: Pediatrics
https://www.readbyqxmd.com/read/28604169/health-effects-of-overweight-and-obesity-in-195-countries-over-25-years
#4
Ashkan Afshin, Mohammad H Forouzanfar, Marissa B Reitsma, Patrick Sur, Kara Estep, Alex Lee, Laurie Marczak, Ali H Mokdad, Maziar Moradi-Lakeh, Mohsen Naghavi, Joseph S Salama, Theo Vos, Kalkidan H Abate, Cristiana Abbafati, Muktar B Ahmed, Ziyad Al-Aly, Ala’a Alkerwi, Rajaa Al-Raddadi, Azmeraw T Amare, Alemayehu Amberbir, Adeladza K Amegah, Erfan Amini, Stephen M Amrock, Ranjit M Anjana, Johan Ärnlöv, Hamid Asayesh, Amitava Banerjee, Aleksandra Barac, Estifanos Baye, Derrick A Bennett, Addisu S Beyene, Sibhatu Biadgilign, Stan Biryukov, Espen Bjertness, Dube J Boneya, Ismael Campos-Nonato, Juan J Carrero, Pedro Cecilio, Kelly Cercy, Liliana G Ciobanu, Leslie Cornaby, Solomon A Damtew, Lalit Dandona, Rakhi Dandona, Samath D Dharmaratne, Bruce B Duncan, Babak Eshrati, Alireza Esteghamati, Valery L Feigin, João C Fernandes, Thomas Fürst, Tsegaye T Gebrehiwot, Audra Gold, Philimon N Gona, Atsushi Goto, Tesfa D Habtewold, Kokeb T Hadush, Nima Hafezi-Nejad, Simon I Hay, Masako Horino, Farhad Islami, Ritul Kamal, Amir Kasaeian, Srinivasa V Katikireddi, Andre P Kengne, Chandrasekharan N Kesavachandran, Yousef S Khader, Young-Ho Khang, Jagdish Khubchandani, Daniel Kim, Yun J Kim, Yohannes Kinfu, Soewarta Kosen, Tiffany Ku, Barthelemy Kuate Defo, G Anil Kumar, Heidi J Larson, Mall Leinsalu, Xiaofeng Liang, Stephen S Lim, Patrick Liu, Alan D Lopez, Rafael Lozano, Azeem Majeed, Reza Malekzadeh, Deborah C Malta, Mohsen Mazidi, Colm McAlinden, Stephen T McGarvey, Desalegn T Mengistu, George A Mensah, Gert B M Mensink, Haftay B Mezgebe, Erkin M Mirrakhimov, Ulrich O Mueller, Jean J Noubiap, Carla M Obermeyer, Felix A Ogbo, Mayowa O Owolabi, George C Patton, Farshad Pourmalek, Mostafa Qorbani, Anwar Rafay, Rajesh K Rai, Chhabi L Ranabhat, Nikolas Reinig, Saeid Safiri, Joshua A Salomon, Juan R Sanabria, Itamar S Santos, Benn Sartorius, Monika Sawhney, Josef Schmidhuber, Aletta E Schutte, Maria I Schmidt, Sadaf G Sepanlou, Moretza Shamsizadeh, Sara Sheikhbahaei, Min-Jeong Shin, Rahman Shiri, Ivy Shiue, Hirbo S Roba, Diego A S Silva, Jonathan I Silverberg, Jasvinder A Singh, Saverio Stranges, Soumya Swaminathan, Rafael Tabarés-Seisdedos, Fentaw Tadese, Bemnet A Tedla, Balewgizie S Tegegne, Abdullah S Terkawi, J S Thakur, Marcello Tonelli, Roman Topor-Madry, Stefanos Tyrovolas, Kingsley N Ukwaja, Olalekan A Uthman, Masoud Vaezghasemi, Tommi Vasankari, Vasiliy V Vlassov, Stein E Vollset, Elisabete Weiderpass, Andrea Werdecker, Joshua Wesana, Ronny Westerman, Yuichiro Yano, Naohiro Yonemoto, Gerald Yonga, Zoubida Zaidi, Zerihun M Zenebe, Ben Zipkin, Christopher J L Murray
BACKGROUND: Although the rising pandemic of obesity has received major attention in many countries, the effects of this attention on trends and the disease burden of obesity remain uncertain. METHODS: We analyzed data from 68.5 million persons to assess the trends in the prevalence of overweight and obesity among children and adults between 1980 and 2015. Using the Global Burden of Disease study data and methods, we also quantified the burden of disease related to high body-mass index (BMI), according to age, sex, cause, and BMI in 195 countries between 1990 and 2015...
July 6, 2017: New England Journal of Medicine
1
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"