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JOURNAL ARTICLE
REVIEW
[Topiramate, a new antiepileptic drug].
Revista de Neurologia 1997 August
OBJECTIVE: The characteristics of the new anti-epileptic drug topiramato (TPM) are described: multiple mechanism of action, favourable pharmaco-kinetics, wide therapeutic range and is relatively well tolerated, Development. Its initial usefulness in patients with partial crises resistant to other anti-epileptic drugs has been shown. TPM is equally effective in primary generalized crises, and in patients with the Lennox-Gastaut syndrome, in whom no problem of tolerance has been seen.
CONCLUSION: TPM is a valuable drug for the treatment of epilepsy.
CONCLUSION: TPM is a valuable drug for the treatment of epilepsy.
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