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JOURNAL ARTICLE
RANDOMIZED CONTROLLED TRIAL
[Evaluation of the treatment of symptomatic urinary tract infection with a single dose of antibiotics or bicarbonate].
Schweizerische Medizinische Wochenschrift 1983 January 9
68 women with acute, uncomplicated urinary tract infection confirmed bacteriologically were randomized to receive either a single oral dose of cotrimoxazole, a single oral dose of amoxycillin, or an oral dose of Na-bicarbonate. Results comparable to previous reports were obtained with the cotrimoxazole regimen. On the other hand, the efficacy of single-dose amoxycillin appeared to be inferior. It is possible that pharmacocinetic differences influence the efficacy of these drugs.
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