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Exploiting iron metabolism as a therapeutic vulnerability in glioblastoma.
Clinical Cancer Research 2023 November 21
In this CCR Translations, we discuss pharmacological ascorbate as a novel therapeutic for glioblastoma. Aberrant iron metabolism in glioblastoma can be assessed noninvasively by MRI and exploited to potentially improve the efficacy of chemoradiotherapy. We contextualize the study's results and discuss the next steps to further develop this paradigm.
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