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Multisystem approach for management of OSA in Down syndrome: a case report.
Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine 2023 November 9
Obstructive sleep apnea (OSA) is common in children with Down syndrome (DS), with reported prevalence rates as high as 69-76%. Multiple factors predispose children with DS for OSA including craniofacial hypoplasia (maxillary and mandibular), airway abnormalities, macroglossia, generalized hypotonia, airway hypotonia, adenotonsillar hypertrophy, and obesity. Despite the pathophysiology for OSA in children with DS being multifactorial in nature, treatment methods have focused on soft tissue in the upper airway using adenotonsillectomy and/or continuous positive airway pressure therapy (CPAP). Here we present a case of a patient with DS whose severe OSA was approached in a multisystem manner including upper airway soft tissue, orthognathic, maxillofacial, and bariatric surgery, resulting in resolution of the OSA without reliance on a continuous positive airway pressure (CPAP) device.
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