Long-term results of sexual function and body image after vaginoplasty with acellular dermal matrix in women with Mayer-Rokitansky-Küster-Hauser Syndrome.

STUDY OBJECTIVE: To describe the long-term anatomic and sexual functional results of vaginoplasty with ADM in patients with MRKH and to evaluate the changes in body image pre- and postoperatively in these patients.

DESIGN: Retrospective study from March 2015 to September 2021.

SETTING: Tertiary teaching hospital.

PATIENTS: Forty-two patients with MRKH syndrome who underwent vaginoplasty with acellular dermal matrix (ADM) (the MRKH group) and 30 sexually active, nulliparous, aged-matched women (the control group).

INTERVENTION: The relevant data were retrospectively collected via our electronic medical record system and were analysed statistically.

MEASUREMENTS AND MAIN RESULTS: Vaginal length was assessed using a 3-cm-diameter mould. The Chinese version of the Female Sexual Function Index (FSFI) questionnaire was used to evaluate sexual function. The Chinese version of the modified body image scale (MBIS) was applied to evaluate body image. The median follow-up time was 57 months (range 13-91 months). Granulomatous polyps in the neovagina were the most common postoperative complication (7/42, 16.7%). MRKH patients can achieve long-term satisfactory outcomes both anatomically and functionally after vaginoplasty with ADM, comparable to those of healthy control women. The MBIS score was significantly decreased after vaginoplasty with ADM.

CONCLUSION: Vaginoplasty with ADM is a minimally invasive and effective procedure for patients with MRKH syndrome.