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JOURNAL ARTICLE
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[Topography of carcinoma in situ and carcinoma with minimal invasion of the uterine cervix].

There were 160 coni histologically analysed in which carcinoma in situ (CIS) or carcinoma cum invasione minimali (CIM) were diagnosed. Their most frequent localization was the transitional zone. CIS was spreading in 95.4% of cases to the transitional zone, in 67.4% to the part covered with a cylindrical epithelium, and in 19.8% to the part covered with a squamous epithelium. CIM was found to have affected the transitional zone in 90.5%, the cervical zone covered with a cylindrical epithelium in 78.4% and the zone partly covered with a squamous epithelium in 52.7% of cases. CIS was spread to both cervical labia in 65.1% of cases--to the front labium in 23.3% and the back labium in 11.6% of cases. CIM was found to have affected both labia in 90.5% of cases--the front labium in 6.7% and the back labium in 2.7% of cases. CIS and CIM were formed from three types of cells, i.e. types A, B, and C. Both CIS and CIM formed from type A were located in the zone of the squamous epithelium in the portio, those formed from type C endocervically, and those from type B in--between. There were also carcinomas formed from two or three cell types. In the mixed types of carcinoma, type C cells were never found in the portio, nor type A cells in the endo-cervix.

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