[The synchronous detection of serological markers of main herpes viral human infections].

The new original national set of reagents "Line-Blot human herpesvirus-profle" was developed to detect antibodies (IgG - set 1 and IgM - set 2) to main agents of herpesvirus infections (HSV-1, HSV-2, VZV, EBV, CMV) in the format of linear immunoblotting. The preliminary clinical trials were implemented using 319 samples of blood serum: HIV-infected patients (n=128), pregnant women (n=86) and persons undergoing treatment or diagnostic examination (n=105). In the case of every infection agent analyzes were implemented using enzyme-linked immunosorbent assay and linear immunoblotting with new set and its analogues of German manufacturer. The indices of diagnostic informativeness were calculated according GOST R 53022.3-2008. The obtained data permitted to begin registration in the Russian Federation the new set of reagents intended to synchronous screening of monospecifc antibodies to main agents of human herpesviral infections and establishment of activity of manifestation of infection and time of infection by some of them.