Ways to increase adherence to allergen immunotherapy.

Adherence to allergen immunotherapy (AIT) is crucial for its efficacy. Subcutaneous AIT requires monthly visits (or more extended in the case of venom immunotherapy), while sublingual is performed with a daily intake of allergen drops. Non-adherence to an AIT schedule and premature discontinuation are common problems. Results from various studies have concluded to controversial results on the rate of AIT adherence. The aim of this review was to describe the problem of non-adherence and to offer some evidence-based advice to allergologists, on how to increase it. Better patient education at the beginning of treatment, sharing with patient the decision on which type of immunotherapy to select, and showing sincere interest on their treatment concerns are some tips that can help to increase adherence. A well-organized allergologist time schedule not only increases safety but also offers the possibility of close follow-up and an increase in patient loyalty.