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ENGLISH ABSTRACT
JOURNAL ARTICLE
[Progress on medication-related osteonecrosis of the jaw].
Hua Xi Kou Qiang Yi Xue za Zhi = Huaxi Kouqiang Yixue Zazhi = West China Journal of Stomatology 2018 October 2
Medication-related osteonecrosis of the jaw (MRONJ) is a severe complication of bisphosphonates (BPs) or other targeted agent therapies. MRONJ appears as exposed bone, pus, and swelling in the oral and maxillofacial regions. However, neither surgery nor conservative therapy can eliminate symptoms thoroughly. In addition to BPs, several antiresorptive and antiangiogenic agents, such as denosumab and bevacizumab, as well as targeted agents, such as sunitinib and temsirolimus, can cause osteonecrosis of the jaw according to the literature. This review aims to summarize the research progress on these new drugs.
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