First evidence of cytotoxic effects of human protozoan parasites on zebra mussel (Dreissena polymorpha) hemocytes.

The interaction between human protozoan parasites and the immune cells of bivalves, that can accumulate them, is poorly described. The purpose of this study is to consider the mechanisms of action of some of these protozoa on zebra mussel hemocytes, by evaluating their cytotoxic potential. Hemocytes were exposed to Toxoplasma gondii, Giardia duodenalis or Cryptosporidium parvum (oo)cysts. The results showed a cytotoxic potency of the two largest protozoa on hemocytes, and suggested the formation of hemocyte aggregates. Thus, this study reveals the first signs of a hemocyte:protozoan interaction. This article is protected by copyright. All rights reserved.