Multivariate analysis of potential risk factors for lymph node metastasis in patients with cutaneous squamous cell carcinoma of the head and neck.

Risk factors for metastasis from cutaneous squamous cell carcinoma are incorporated in tumor staging by the seventh edition of the American Joint Committee on Cancer Cancer Staging Manual.We confirmed most risk factors, and also identified moderate differentiation as a predictor for lymph node metastasis. Moderate differentiation can be considered in tumor staging.