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Evaluation of four algorithms to identify incident syphilis among HIV-positive men who have sex with men engaged in primary care.

We developed four algorithms for syphilis among HIV-positive MSM engaged in primary care in 2016-2017. Clinician-based diagnosis from chart reviews was the gold standard. Sensitivities ranged from 74.2% to 93.9%. Specificities were >99% with positive and negative predictive values >95%. Algorithms that incorporated treatment data performed best.

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