We have located links that may give you full text access.
JOURNAL ARTICLE
META-ANALYSIS
SYSTEMATIC REVIEW
Meta-analysis of the association between chromosomal polymorphisms and outcomes of embryo transfer following in vitro fertilization and/or intracytoplasmic sperm injection.
International Journal of Gynaecology and Obstetrics 2019 Februrary
BACKGROUND: The outcomes of in vitro fertilization and/or intracytoplasmic sperm injection (IVF/ICSI) are contradictory among individuals with chromosomal polymorphisms.
OBJECTIVES: To assess whether chromosomal polymorphisms affect the outcomes of assisted reproductive technologies.
SEARCH STRATEGY: Four online databases were searched from inception to September 18, 2017, using terms including "chromosomal polymorphisms" and "In vitro fertilization."
SELECTION CRITERIA: The meta-analysis included studies published in any language on IVF/ICSI outcomes in relation to male and/or female chromosomal polymorphisms (n=8).
DATA COLLECTION AND ANALYSIS: Data were extracted using a predesigned form. The IVF/ICSI outcomes were then pooled and their heterogeneity assessed.
MAIN RESULTS: Male chromosomal polymorphisms showed lowered values for fertilization rate (odds ratio [OR] 1.29, 95% confidence interval [CI] 1.09-1.54; P=0.004); cleavage rate (OR 2.65, 95% CI 1.88-3.72; P<0.001); good quality embryos rate (OR 1.26, 95% CI 1.15-1.39; P<0.001); and live birth rate (OR 1.42, 95% CI 1.10-1.83; P=0.007). By contrast, early spontaneous abortion rate, clinical pregnancy rate, and ongoing pregnancy rate were not affected in this group. No relationship was found between IVF/ICSI outcomes and female chromosomal polymorphisms.
CONCLUSIONS: Male, but not female, chromosomal polymorphisms were associated with lowered values for some outcomes of IVF/ICSI.
OBJECTIVES: To assess whether chromosomal polymorphisms affect the outcomes of assisted reproductive technologies.
SEARCH STRATEGY: Four online databases were searched from inception to September 18, 2017, using terms including "chromosomal polymorphisms" and "In vitro fertilization."
SELECTION CRITERIA: The meta-analysis included studies published in any language on IVF/ICSI outcomes in relation to male and/or female chromosomal polymorphisms (n=8).
DATA COLLECTION AND ANALYSIS: Data were extracted using a predesigned form. The IVF/ICSI outcomes were then pooled and their heterogeneity assessed.
MAIN RESULTS: Male chromosomal polymorphisms showed lowered values for fertilization rate (odds ratio [OR] 1.29, 95% confidence interval [CI] 1.09-1.54; P=0.004); cleavage rate (OR 2.65, 95% CI 1.88-3.72; P<0.001); good quality embryos rate (OR 1.26, 95% CI 1.15-1.39; P<0.001); and live birth rate (OR 1.42, 95% CI 1.10-1.83; P=0.007). By contrast, early spontaneous abortion rate, clinical pregnancy rate, and ongoing pregnancy rate were not affected in this group. No relationship was found between IVF/ICSI outcomes and female chromosomal polymorphisms.
CONCLUSIONS: Male, but not female, chromosomal polymorphisms were associated with lowered values for some outcomes of IVF/ICSI.
Full text links
Related Resources
Trending Papers
Heart failure with preserved ejection fraction: diagnosis, risk assessment, and treatment.Clinical Research in Cardiology : Official Journal of the German Cardiac Society 2024 April 12
Proximal versus distal diuretics in congestive heart failure.Nephrology, Dialysis, Transplantation 2024 Februrary 30
World Health Organization and International Consensus Classification of eosinophilic disorders: 2024 update on diagnosis, risk stratification, and management.American Journal of Hematology 2024 March 30
Efficacy and safety of pharmacotherapy in chronic insomnia: A review of clinical guidelines and case reports.Mental Health Clinician 2023 October
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app