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JOURNAL ARTICLE
Basal Instinct: Persistence of Barrier Dysfunction.
Immunity 2018 October 17
In a recent issue of Nature, Ordovas-Montanes et al. (2018) used cutting-edge genomic, epigenetic, and interventional techniques to characterize the cellular ecosystem in allergic chronic rhinosinusitis. They showed that basal epithelial cells "remember" type 2 inflammatory stimuli to maintain a chronic allergic disease phenotype.
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