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Natural Killer Cell-Based Cancer Immunotherapy: A Review on 10 Years Completed Clinical Trials.

Wade Chun-Wai Suen, Wayne Yuk-Wai Lee, Kam-Tong Leung, Xiao-Hua Pan, Gang Li
Cancer Investigation 2018
NK cell cancer immunotherapy is an emerging anti-tumour therapeutic strategy that explores NK cell stimulation. In this review, we address strategies developed to circumvent limitations to clinical application of NK cell-based therapies, and comprehensively review the design and results of clinical trials conducted in the past 10 years (2008-2018) to test their therapeutic potential. NK cell-based immunotherapy of solid cancers remains controversial, but merit further detailed investigation.

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