We have located links that may give you full text access.
Psychiatric comorbidity in persons with high-functioning autism spectrum disorders: Findings from a tertiary care neuropsychiatric hospital.
Asian Journal of Psychiatry 2019 March
BACKGROUND: The literature on co-morbid psychiatric illnesses in adults with high-functioning autism (HFA) spectrum disorder is sparse.
PURPOSE: To examine the nature of psychiatric comorbidity and treatment response in adults with HFA spectrum disorder.
MATERIALS AND METHODS: Case records of subjects (age ≥17 years) who presented over a period of 16 years with primary psychiatric symptoms and further detected to have an HFA spectrum disorder, were analyzed. Autism spectrum disorders (ASD) along with near normal to normal verbal communication and general intelligence were considered as HFA spectrum disorders.
RESULTS: 33 subjects met the study criteria. Nine subjects (27%) were diagnosed to have an underlying Asperger's syndrome and the rest 24 (73%) had pervasive developmental disorders unspecified (PDD NOS). None of the subjects were diagnosed to be suffering from ASD prior to the visit to our hospital. Mean age at the time of psychiatric consultation was 22.7 (s.d=4.8) years and mean age at the onset of psychiatric comorbidity was 16.48 (s.d=4.4) years. Nearly half of the sample had more than one type of psychiatric illness. Most common lifetime psychiatric diagnosis was obsessive-compulsive disorder (OCD) (n=16, 48.4%). Bipolar disorder (BD) was the second most common type of psychiatric manifestation (n=13, 39.3%) followed by psychotic spectrum disorders (n=9, 27.2%). Overall response to treatment was minimal.
CONCLUSIONS: Individuals with HFA spectrum disorders suffer from multiple psychiatric comorbidities. OCD is the most common type of psychiatric comorbidity followed by BD and psychotic spectrum disorders. Comorbid psychiatric illnesses in individuals with HFA show poor response to treatment.
PURPOSE: To examine the nature of psychiatric comorbidity and treatment response in adults with HFA spectrum disorder.
MATERIALS AND METHODS: Case records of subjects (age ≥17 years) who presented over a period of 16 years with primary psychiatric symptoms and further detected to have an HFA spectrum disorder, were analyzed. Autism spectrum disorders (ASD) along with near normal to normal verbal communication and general intelligence were considered as HFA spectrum disorders.
RESULTS: 33 subjects met the study criteria. Nine subjects (27%) were diagnosed to have an underlying Asperger's syndrome and the rest 24 (73%) had pervasive developmental disorders unspecified (PDD NOS). None of the subjects were diagnosed to be suffering from ASD prior to the visit to our hospital. Mean age at the time of psychiatric consultation was 22.7 (s.d=4.8) years and mean age at the onset of psychiatric comorbidity was 16.48 (s.d=4.4) years. Nearly half of the sample had more than one type of psychiatric illness. Most common lifetime psychiatric diagnosis was obsessive-compulsive disorder (OCD) (n=16, 48.4%). Bipolar disorder (BD) was the second most common type of psychiatric manifestation (n=13, 39.3%) followed by psychotic spectrum disorders (n=9, 27.2%). Overall response to treatment was minimal.
CONCLUSIONS: Individuals with HFA spectrum disorders suffer from multiple psychiatric comorbidities. OCD is the most common type of psychiatric comorbidity followed by BD and psychotic spectrum disorders. Comorbid psychiatric illnesses in individuals with HFA show poor response to treatment.
Full text links
Related Resources
Trending Papers
Challenges in Septic Shock: From New Hemodynamics to Blood Purification Therapies.Journal of Personalized Medicine 2024 Februrary 4
Molecular Targets of Novel Therapeutics for Diabetic Kidney Disease: A New Era of Nephroprotection.International Journal of Molecular Sciences 2024 April 4
The 'Ten Commandments' for the 2023 European Society of Cardiology guidelines for the management of endocarditis.European Heart Journal 2024 April 18
A Guide to the Use of Vasopressors and Inotropes for Patients in Shock.Journal of Intensive Care Medicine 2024 April 14
Diagnosis and Management of Cardiac Sarcoidosis: A Scientific Statement From the American Heart Association.Circulation 2024 April 19
Essential thrombocythaemia: A contemporary approach with new drugs on the horizon.British Journal of Haematology 2024 April 9
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app