Add like
Add dislike
Add to saved papers

Rh-Catalyzed Removable Directing Group Assisted sp2 or sp3-C-H Bond Functionalization.

Angewandte Chemie 2018 October 13
In recent years, transition-metal-catalyzed C-H activation has become a key strategy in the field of organic synthesis. Among the various transition metal complexes, rhodium complexes are widely used as catalysts in a variety of C-H functionalization reactions due to their high reactivity and selectivity. In addition, because a number of rhodium complexes in various oxidation states are available, this results in diverse reaction patterns. Regioselectivity, an important issue in C-H activation chemistry, can be accomplished by using a directing group to assist the reaction. However, to obtain target functionalized compounds, it is also necessary to use a directing group that can be easily removed. Removable directing group-assisted C-H activation by rhodium catalysts has given us a fruitful combination for achieving certain types of functionalization reactions. Hence, a wide range of directed-C-H functionalization reactions catalyzed by rhodium complexes has been reported to date. In this review, we discuss Rh-catalyzed C-H functionalization reactions that are aided by the use of a removable directing group such as phenol, amine, aldehyde, ketones, ester, acid, sulfonic acid, and N-heteroaromatic derivatives.

Full text links

We have located links that may give you full text access.
Can't access the paper?
Try logging in through your university/institutional subscription. For a smoother one-click institutional access experience, please use our mobile app.

For the best experience, use the Read mobile app

Mobile app image

Get seemless 1-tap access through your institution/university

For the best experience, use the Read mobile app

All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.

By using this service, you agree to our terms of use and privacy policy.

Your Privacy Choices Toggle icon

You can now claim free CME credits for this literature searchClaim now

Get seemless 1-tap access through your institution/university

For the best experience, use the Read mobile app